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Autologous platelet rich plasma after third molar surgery: a comparative study
Ruchi Pathak Kaul1, Suhas S Godhi, Anurag Singh
1Department of Oral& Maxillofacial Surgery, ITS-CDSR, Muradnagar, Ghaziabad, India.
Journal of Maxillofacial and Oral Surgery
|June 5, 2013
Summary
Autologous platelet-rich plasma (PRP) enhances bone regeneration and wound healing in third molar extraction sites. This study found PRP significantly reduced alveolar bone loss and probing depth, promoting faster healing.
Area of Science:
- Oral surgery
- Regenerative medicine
- Biomaterials
Background:
- Third molar extractions can lead to complications like delayed healing.
- Autologous platelet-rich plasma (PRP) is explored for its regenerative potential.
Purpose of the Study:
- To evaluate autologous platelet-rich plasma (PRP) for wound healing and bone regeneration in human third molar extraction sockets.
Main Methods:
- PRP was prepared and applied to extraction sockets of impacted mandibular third molars.
- Radiographs assessed wound dehiscence, probing depth, bone density, and alveolar bone levels post-operatively.
Main Results:
- PRP grafted sockets showed 8% dehiscence.
- Significant decrease in alveolar bone level and probing depth observed in PRP groups at 3 and 6 months.
- Enhanced bone formation and density in PRP grafted sockets compared to controls.
Conclusions:
- PRP is an effective, inexpensive option for improving hard and soft tissue healing post-extraction.
- Autologous nature of PRP avoids immunogenic reactions and disease transmission.
- PRP shows promise in tissue engineering for dental applications.
