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Updated: May 10, 2026
09:33
Three-dimensional Rendering and Analysis of Immunolabeled, Clarified Human Placental Villous Vascular Networks
Published on: March 29, 2018
[Placental MRI: physiology and pathology]
B Deloison1, A-E Millischer, L-J Salomon
1Service de gynécologie-obstétrique et de médecine fœtale, université Paris Descartes, Sorbonne Paris-Cité, hôpital Necker-Enfants-Malades, Assistance publique-Hôpitaux de Paris, 149 rue de Sèvres, Paris, France. benjamindeloison@hotmail.com
Gynecologie, Obstetrique & Fertilite
|June 5, 2013
Summary
Magnetic Resonance Imaging (MRI) offers a safe, non-invasive method to study placental function and anatomy. Advanced MRI techniques can precisely assess placental health in vivo, aiding in the diagnosis of conditions like IUGR and preeclampsia.
Area of Science:
- Obstetrics and Gynecology
- Medical Imaging
- Fetal Development
Context:
- In vivo study of placental function and perfusion is limited.
- Placental function is altered in conditions like intrauterine growth restriction (IUGR) and preeclampsia.
- Placental anatomy, such as in placenta accreta, requires better in vivo assessment.
Purpose:
- To highlight the potential of Magnetic Resonance Imaging (MRI) for studying placental function and anatomy.
- To introduce advanced MRI sequences as novel tools for in vivo placental assessment.
- To explore MRI's role in understanding and diagnosing placental abnormalities.
Summary:
- Magnetic Resonance Imaging (MRI) provides a safe, non-invasive window into placental development and health.
- Advanced MRI sequences including Dynamic Contrast-Enhanced (DCE), Intravoxel Incoherent Motion (IVIM), Blood Oxygen Level Dependent (BOLD), and Arterial Spin Labeling (ASL) offer new capabilities.
- These techniques enable precise, in vivo evaluation of placental perfusion, function, and anatomy, which are crucial for fetal development.
Impact:
- MRI can significantly improve the understanding and clinical management of pregnancy complications.
- Non-invasive assessment of placental perfusion and function can lead to earlier diagnosis and intervention.
- This research paves the way for enhanced prenatal care through advanced imaging modalities.
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