Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Factors Affecting Respiration01:24

Factors Affecting Respiration

Respiration is a crucial physiological function involving exchanging oxygen (O2) and carbon dioxide (CO2) between an organism and its environment. Various factors can impact this essential process:
Metabolic Rate01:25

Metabolic Rate

The human body is a powerhouse of energy, with every cell performing numerous functions that require energy. This energy production and consumption is measured by the metabolic rate, which quantifies the total heat generated by all the body's chemical reactions and mechanical work. This measurement helps to determine the rate of kilocalorie (kcal) consumption needed to fuel all ongoing activities.
The Basal Metabolic Rate (BMR) measures the energy expended at rest.
Several factors influence the...
Factors Affecting Body Temperature01:28

Factors Affecting Body Temperature

As a nurse, it is vital to understand the factors affecting body temperature to monitor variations and effectively evaluate deviations from regular.
Factors may  include:
Requirements for Human Life01:26

Requirements for Human Life

The Earth and its atmosphere have provided humans with air, water, and food, but these are not the only requirements for survival. Humans also require a specific range of temperature and pressure that the Earth and its atmosphere provides.
Oxygen
Atmospheric air is only about 20 percent oxygen, but that oxygen is a key component of the chemical reactions that keep the body alive, including the reactions that produce ATP. Brain cells are susceptible to a lack of oxygen because they require a...
Other Factors Affecting Respiration Centers01:17

Other Factors Affecting Respiration Centers

Breathing is primarily an involuntary activity regulated by the brainstem respiratory centers. However, it can also be consciously controlled, allowing us to hold our breath or take deeper breaths when needed. This voluntary control is facilitated by the cerebral motor cortex, which bypasses the medullary centers to stimulate the respiratory muscles directly.
However, the ability to hold one's breath voluntarily is not limitless. When the CO2 concentration in the blood reaches a critical level,...
Factors Influencing Microbial Growth: Temperature01:27

Factors Influencing Microbial Growth: Temperature

Microorganisms display remarkable adaptations, enabling them to thrive in diverse ecological niches across a wide range of temperatures. Temperature profoundly influences microbial growth by affecting enzymatic activity, membrane fluidity, and other cellular processes.Each microorganism operates within a specific temperature range defined by three cardinal points: minimum, optimum, and maximum. Below the minimum temperature, membranes lose fluidity, halting transport processes. Above the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The Mouse-To-Elephant Metabolic Curve: Historical Overview.

Comprehensive Physiology·2023
Same author

Breath-by-breath analysis of respiratory sinus arrhythmia in dogs.

Respiratory physiology & neurobiology·2021
Same author

Social interaction and the thermogenic response of chicken hatchlings.

Physiology & behavior·2021
Same author

Respiratory sinus arrhythmia during a mental attention task: the role of breathing-specific heart rate.

Respiratory physiology & neurobiology·2019
Same author

Hypoxic hypometabolism in chicken embryos: conformism and downregulation.

Comparative biochemistry and physiology. Part A, Molecular & integrative physiology·2019
Same author

Behavioral thermoregulation in avian embryos: Spectrum analysis of calls in warm and cold conditions.

Behavioural processes·2019
Same journal

The Evolution of Taste: Genetic, Dietary, and Cultural Pathways in Human Taste Perception.

Comprehensive Physiology·2026
Same journal

SLIT-ROBO Signaling in Diabetes: A Dual Regulator of Angiogenesis and Vascular Dysfunction.

Comprehensive Physiology·2026
Same journal

Heart-Specific Spinal and Vagal Afferents: Transcriptomic Signatures and Optogenetically Modulated Functional Coupling With Cardiomyocytes.

Comprehensive Physiology·2026
Same journal

The Adipose-Organ Communication Network in Clinical Obesity: From Adiposopathy to Systemic Metabolic Failure.

Comprehensive Physiology·2026
Same journal

Insight Into the Biological Link Between Novel Adiposity Indices and Incident Heart Failure.

Comprehensive Physiology·2026
Same journal

Domino Effect of the Kynurenine Pathway: Systemic Homeostasis, Metabolic Crosstalk, and Therapeutic Potential.

Comprehensive Physiology·2026
See all related articles

Related Experiment Video

Updated: May 10, 2026

Temperature Response of Soil Organic Matter Decomposition Rates: Construction and Applications of a Temperature Gradient Block
07:46

Temperature Response of Soil Organic Matter Decomposition Rates: Construction and Applications of a Temperature Gradient Block

Published on: January 30, 2026

Metabolism, temperature, and ventilation.

Jacopo P Mortola1, Michael Maskrey

  • 1Department of Physiology, McGill University, Montreal, Canada. jacopo.mortola@mcgill.ca

Comprehensive Physiology
|June 5, 2013
PubMed
Summary
This summary is machine-generated.

Pulmonary ventilation (VE) closely matches oxygen consumption (VO2) in mammals and birds, but thermal conditions and CO2 elimination can alter this relationship. Arterial CO2 stability suggests CO2 links metabolic rate to VE.

More Related Videos

Simulating Temperature in a Soil Incubation Experiment
08:39

Simulating Temperature in a Soil Incubation Experiment

Published on: October 28, 2022

Calorespirometry: A Powerful, Noninvasive Approach to Investigate Cellular Energy Metabolism
09:08

Calorespirometry: A Powerful, Noninvasive Approach to Investigate Cellular Energy Metabolism

Published on: May 31, 2018

Related Experiment Videos

Last Updated: May 10, 2026

Temperature Response of Soil Organic Matter Decomposition Rates: Construction and Applications of a Temperature Gradient Block
07:46

Temperature Response of Soil Organic Matter Decomposition Rates: Construction and Applications of a Temperature Gradient Block

Published on: January 30, 2026

Simulating Temperature in a Soil Incubation Experiment
08:39

Simulating Temperature in a Soil Incubation Experiment

Published on: October 28, 2022

Calorespirometry: A Powerful, Noninvasive Approach to Investigate Cellular Energy Metabolism
09:08

Calorespirometry: A Powerful, Noninvasive Approach to Investigate Cellular Energy Metabolism

Published on: May 31, 2018

Area of Science:

  • Physiology
  • Respiratory System
  • Thermoregulation

Background:

  • Oxygen consumption (VO2) and pulmonary ventilation (VE) are coupled in mammals and birds.
  • VE also facilitates CO2 elimination, creating potential conflicts with O2 convection.
  • Respiratory system aids in body temperature and water balance, especially in thermal extremes.

Purpose of the Study:

  • To examine the relationship between VE and VO2 under thermal stimuli.
  • To investigate how hypoxia, hypercapnia, and metabolic rate changes influence this relationship.
  • To explore the link between metabolic rate and VE, focusing on CO2's role.

Main Methods:

  • Analysis of existing physiological data on VE and VO2.
  • Examination of breathing patterns and alveolar ventilation adjustments.
  • Review of studies involving thermal challenges, hypoxia, and hypercapnia.

Main Results:

  • VE and VO2 show close coupling when gas exchange is the primary focus.
  • Thermal conditions and other physiological demands can decouple VE from VO2.
  • Arterial CO2 levels remain remarkably stable across various metabolic and environmental conditions.

Conclusions:

  • The respiratory system balances multiple demands, including gas exchange, thermoregulation, and water balance.
  • CO2, rather than parallel control mechanisms, likely links metabolic rate to pulmonary ventilation.
  • Understanding this link is crucial for respiratory physiology and its regulation.