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Updated: May 10, 2026

Evaluation of Mammary Gland Development and Function in Mouse Models
Published on: July 21, 2011
Prenatal morphogenesis of mammary glands in mouse and rabbit
Alain Y Propper1, Beatrice A Howard, Jacqueline M Veltmaat
1Laboratoire de Neurosciences, EA481, Université de Franche-Comté, (Emeritus), 25030, Besançon Cedex, France.
Abstract:
Our understanding of prenatal morphogenesis of mammary glands has recently greatly advanced. This review focuses on morphogenesis proper, as well as cellular processes and tissue interactions involved in the progression of the embryonic mammary gland through sequential morphogenic stages in both the mouse and rabbit embryo. We provide a synthesis of both historical and more recent studies of embryonic mammary gland development, as well as arguments to revise old concepts about mechanisms of mammary line and rudiment formation. Finally, we highlight outstanding issues that remain to be addressed.

