Jove
Visualize
Contact Us

Related Concept Videos

Modified-Release Drug Delivery Systems: Stimuli-Activated01:30

Modified-Release Drug Delivery Systems: Stimuli-Activated

Stimuli-activated drug delivery systems are designed to release drugs in response to specific physical, chemical, or biological stimuli. These systems often utilize hydrogels—three-dimensional, hydrophilic polymer networks capable of swelling in aqueous environments and retaining significant fluid volumes. Upon exposure to particular stimuli, these hydrogels undergo structural transitions that allow the embedded drug to be released. Due to this adaptive behavior, such systems are also called...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Synergistic Solvent-Surface Interactions Enable Alkyne Semihydrogenation at Palladium.

ACS applied materials & interfaces·2026
Same author

Scalable Manufacturing of Amino Acid-Based Piezoelectric Biocrystal Films.

Small (Weinheim an der Bergstrasse, Germany)·2026
Same author

Kilohertz linewidth VCSEL with an external high Q-factor intrinsic optical fiber Fabry-Pérot cavity.

Optics express·2026
Same author

CuO/Cu(OH)<sub>2</sub> Heterostructure with Sustained Dynamic Re-equilibration and High HER Activity.

ACS applied materials & interfaces·2026
Same author

Cross-modality representation and multi-sample integration of spatially resolved omics data.

Briefings in bioinformatics·2026
Same author

The characteristics of Chinese household refrigerator microbial communities obtained from different geographical regions and different sampling sites.

Antonie van Leeuwenhoek·2026
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: May 10, 2026

Fabricating Degradable Thermoresponsive Hydrogels on Multiple Length Scales via Reactive Extrusion, Microfluidics, Self-assembly, and Electrospinning
12:07

Fabricating Degradable Thermoresponsive Hydrogels on Multiple Length Scales via Reactive Extrusion, Microfluidics, Self-assembly, and Electrospinning

Published on: April 16, 2018

Stimuli-responsive polymer films.

Lei Zhai1

  • 1NanoScience Technology Center and Department of Chemistry, University of Central Florida, Orlando, USA. lzhai@ucf.edu

Chemical Society Reviews
|June 11, 2013
PubMed
Summary
This summary is machine-generated.

Stimuli-responsive polymer films change structure with external triggers, finding uses in smart coatings and drug delivery. This review covers key components and recent advances in responsive polymer systems.

More Related Videos

Preparation of Thermoresponsive Nanostructured Surfaces for Tissue Engineering
12:22

Preparation of Thermoresponsive Nanostructured Surfaces for Tissue Engineering

Published on: March 1, 2016

Environmentally-controlled Microtensile Testing of Mechanically-adaptive Polymer Nanocomposites for ex vivo Characterization
11:38

Environmentally-controlled Microtensile Testing of Mechanically-adaptive Polymer Nanocomposites for ex vivo Characterization

Published on: August 20, 2013

Related Experiment Videos

Last Updated: May 10, 2026

Fabricating Degradable Thermoresponsive Hydrogels on Multiple Length Scales via Reactive Extrusion, Microfluidics, Self-assembly, and Electrospinning
12:07

Fabricating Degradable Thermoresponsive Hydrogels on Multiple Length Scales via Reactive Extrusion, Microfluidics, Self-assembly, and Electrospinning

Published on: April 16, 2018

Preparation of Thermoresponsive Nanostructured Surfaces for Tissue Engineering
12:22

Preparation of Thermoresponsive Nanostructured Surfaces for Tissue Engineering

Published on: March 1, 2016

Environmentally-controlled Microtensile Testing of Mechanically-adaptive Polymer Nanocomposites for ex vivo Characterization
11:38

Environmentally-controlled Microtensile Testing of Mechanically-adaptive Polymer Nanocomposites for ex vivo Characterization

Published on: August 20, 2013

Area of Science:

  • Polymer Science
  • Materials Science
  • Nanotechnology

Background:

  • Stimuli-responsive polymer films exhibit dynamic structural and property alterations in response to external stimuli.
  • These advanced materials have diverse applications, including smart coatings, controlled drug delivery systems, smart windows, and self-repairing materials.

Purpose of the Study:

  • To review the fundamental principles, including non-covalent bonding, reversible reactions, and responsive molecules, that underpin stimuli-responsive polymer systems.
  • To present recent developments in three key types of responsive polymer systems: layer-by-layer polymer multilayer films, polymer brushes, and self-repairing polymer films.
  • To discuss the response mechanisms associated with these polymer systems.

Main Methods:

  • Review of literature on non-covalent bonding and reversible reactions in polymer science.
  • Analysis of recent advancements in layer-by-layer polymer multilayer films, polymer brushes, and self-repairing polymer films.
  • Discussion of the response mechanisms of various stimuli-responsive polymer systems.

Main Results:

  • Identification of non-covalent bonding, reversible reactions, and responsive molecules as crucial components for stimuli-responsive systems.
  • Overview of recent progress in layer-by-layer polymer multilayer films, polymer brushes, and self-repairing polymer films.
  • Detailed discussion of the response mechanisms governing these polymer systems.

Conclusions:

  • Future research should focus on a deeper understanding of response mechanisms and developing systems with tunable responses to single or multiple stimuli.
  • Integration of polymer film fabrication with nanotechnology and enhancement of film stability on substrates are critical areas for advancement.
  • Evaluation of the toxicity of degradation products is essential for safe and practical applications of these responsive polymer films.