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Related Experiment Video

Updated: May 10, 2026

Combined Invasive Subcortical and Non-invasive Surface Neurophysiological Recordings for the Assessment of Cognitive and Emotional Functions in Humans

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Deep brain stimulation for obsessive-compulsive disorder affects language: a case report.

A Rosaura Polak¹, Anke B Witteveen, Mariska Mantione

¹*Department of Psychiatry and §Department of Neurosurgery, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands; ‡Arq Psychotrauma Expert Group, Diemen, the Netherlands; ¶Netherlands Institute for Neuroscience, an institute of the Royal Netherlands Academy of Arts and Sciences, Amsterdam, the Netherlands.

|June 13, 2013

Summary

This summary is machine-generated.

Deep brain stimulation (DBS) for obsessive-compulsive disorder can temporarily alter speech patterns and vocabulary. These findings offer new insights into brain circuitry and behavioral effects of DBS.

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Area of Science:

Neuroscience
Psychiatry
Neuromodulation

Background:

Deep brain stimulation (DBS) is a therapeutic option for refractory neuropsychiatric disorders.
DBS offers potential insights into brain circuitry functions through observed behavioral effects.

Observation:

Two patients with obsessive-compulsive disorder underwent DBS targeting the nucleus accumbens.
The patients experienced temporary alterations in accent and vocabulary use post-stimulation.

Findings:

Speech changes, including accent shifts, are linked to direct nucleus accumbens stimulation via DBS electrodes.
The observed accent changes resemble foreign accent syndrome, a novel finding in DBS.
Aggressive vocabulary use may correlate with transient hypomanic behavior induced by DBS.

Implications:

DBS may influence language and behavior through specific neural pathways.
This case highlights the complex relationship between brain stimulation, speech, and mood.
Further research is needed to understand the full spectrum of DBS-induced behavioral effects.