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Clinical evaluation of anticalculus dentifrices
Summary
A six-month study found that a 2% zinc citrate toothpaste significantly inhibited calculus formation by 32.3% compared to a placebo. This zinc citrate dentifrice demonstrated superior calculus prevention versus Crest Tartar Control.
Area of Science:
- Oral hygiene
- Dental research
- Preventive dentistry
Background:
- Dental calculus (tartar) is a significant oral health concern.
- Existing dentifrices aim to reduce calculus formation.
- Comparative efficacy of different anti-calculus ingredients requires ongoing investigation.
Purpose of the Study:
- To evaluate the calculus-inhibiting efficacy of a zinc citrate dentifrice.
- To compare the zinc citrate product against Crest Tartar Control and a placebo (Crest Regular).
Main Methods:
- A six-month clinical study involving 187 patients.
- Assessment of calculus inhibition, stain, and soft tissue status.
- Comparison of a 2% zinc citrate/silica dentifrice with Crest Tartar Control and Crest Regular.
Main Results:
- The zinc citrate dentifrice reduced calculus formation by 32.3% compared to the placebo.
- Crest Tartar Control reduced calculus formation by 21.4% compared to the placebo.
- No significant differences were observed in stain or soft tissue status among the groups.
Conclusions:
- Zinc citrate dentifrice demonstrates a statistically significant calculus prevention benefit.
- The 2% zinc citrate/silica product offers superior calculus inhibition compared to the placebo.
- All tested dentifrices were safe and well-tolerated.