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Primary atrophic rhinitis: a clinical profile, microbiological and radiological study
Sampan S Bist1, Manisha Bisht, Jagdish P Purohit
1Department of ENT & Pharmacology, Himalayan Institute of Medical Sciences, Dehradun 248140, India.
ISRN Otolaryngology
|June 14, 2013
Summary
This study on primary atrophic rhinitis found that bacterial infections, anemia, and poor nutrition are significant contributing factors to the condition. Clinical findings include nasal crusting and mucosal atrophy, with sinusitis common on radiological evaluation.
Area of Science:
- Otolaryngology
- Rhinitis Research
- Microbiology
Background:
- Primary atrophic rhinitis presents a complex clinical challenge.
- Understanding its etiology is crucial for effective management.
- Previous research indicates multifactorial causes.
Purpose of the Study:
- To evaluate clinical, microbiological, and radiological features in primary atrophic rhinitis.
- To identify associations between these features and the condition's etiology.
- To investigate potential contributing factors like nutritional status and bacterial infections.
Main Methods:
- Prospective case study design over two years.
- Inclusion of ninety patients diagnosed with primary atrophic rhinitis.
- Comprehensive analysis including complete blood count, total protein, nasal swab microbiology, and radiological evaluation.
Main Results:
- Nasal crusting, odor, and mucosal atrophy were the most consistent clinical findings.
- Low hemoglobin (46.6%) and total protein (25.5%) indicated anemia and malnutrition.
- Pseudomonas aeruginosa was the most frequent isolate (37%), and sinusitis was present in 87.7% of cases.
- Increased nasal mucociliary clearance time and nasal myiasis (26.6%) were also observed.
Conclusions:
- Bacterial infections, particularly Pseudomonas aeruginosa, play a significant role.
- Anemia and poor nutritional status are strongly associated with primary atrophic rhinitis.
- Hereditary factors may also contribute to the etiology of this condition.
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