Related Experiment Video
Updated: May 10, 2026
08:22
Assessment and Characterization of Hyaloid Vessels in Mice
Published on: May 15, 2019
Prepapillary vascular loop associated with persistent hyperplastic primary vitreous
Shinji Makino1, Yuko Ohkubo, Hironobu Tampo
1Department of Ophthalmology, Jichi Medical University, Shimotsuke, 3311-1 Yakushiji, Tochigi 329-0498, Japan.
Case Reports in Ophthalmological Medicine
|June 14, 2013
Summary
This study reports a rare association between prepapillary vascular loops and persistent hyperplastic primary vitreous (PHPV) in a 66-year-old woman. These findings highlight a unique presentation of retinal vascular abnormalities.
Area of Science:
- Ophthalmology
- Vascular Biology
- Retinal Imaging
Background:
- Retinal vessel abnormalities can present asymptomatically.
- Persistent hyperplastic primary vitreous (PHPV) is a congenital developmental anomaly of the eye.
- Prepapillary vascular loops are vascular anomalies located in front of the optic disc.
Purpose of the Study:
- To describe a unique case of bilateral prepapillary vascular loops associated with PHPV.
- To document the clinical presentation and fundus findings in a patient with this rare condition.
Main Methods:
- Case report of a 66-year-old woman.
- Clinical examination including anterior segment and funduscopy.
- Evaluation of retinal vessel abnormality and associated ocular findings.
Main Results:
- The patient presented with a retrolental opacity in the right eye.
- Bilateral prepapillary vascular loops were identified, more prominent in the right eye.
- The vascular loops were associated with PHPV in the right eye, a previously unreported association.
Conclusions:
- This case represents the first reported instance of prepapillary vascular loops associated with PHPV.
- The findings expand the known spectrum of ocular manifestations associated with PHPV.
- Further research may be warranted to understand the pathogenesis of this combined anomaly.
