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Related Concept Videos

Ischemic Stroke ll: Pathophysiology01:15

Ischemic Stroke ll: Pathophysiology

An ischemic stroke occurs when a cerebral blood vessel becomes obstructed, most often by a thrombus or embolus, interrupting the delivery of oxygen and glucose to brain tissue. Because neurons rely on continuous aerobic metabolism, energy failure begins within minutes of reduced perfusion. The region receiving the least blood flow becomes the infarct core, an area of irreversible cellular death. Surrounding this core lies the penumbra, a zone of hypoperfused but still viable tissue that is...

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Related Experiment Video

Updated: May 10, 2026

Integrated Photoacoustic, Ultrasound, and Angiographic Tomography (PAUSAT) for NonInvasive Whole-Brain Imaging of Ischemic Stroke
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Integrated Photoacoustic, Ultrasound, and Angiographic Tomography (PAUSAT) for NonInvasive Whole-Brain Imaging of Ischemic Stroke

Published on: June 2, 2023

CT perfusion in acute stroke: know the mimics, potential pitfalls, artifacts, and technical errors.

Rajiv Mangla1, Sven Ekhom, Babak S Jahromi

  • 1Department of Imaging Sciences, University of Rochester, School of Medicine and Dentistry, 601 Elmwood Avenue, Box 648, Rochester, NY, 14642, USA, rajiv_mangla@urmc.rochester.edu.

Emergency Radiology
|June 18, 2013
PubMed
Summary

Computed tomography perfusion (CTP) imaging aids acute stroke diagnosis but can show abnormalities unrelated to infarct. Understanding CTP mimics and artifacts is crucial for accurate interpretation in neuroimaging.

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Optimized System for Cerebral Perfusion Monitoring in the Rat Stroke Model of Intraluminal Middle Cerebral Artery Occlusion
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Published on: February 17, 2013

Related Experiment Videos

Last Updated: May 10, 2026

Integrated Photoacoustic, Ultrasound, and Angiographic Tomography (PAUSAT) for NonInvasive Whole-Brain Imaging of Ischemic Stroke
06:45

Integrated Photoacoustic, Ultrasound, and Angiographic Tomography (PAUSAT) for NonInvasive Whole-Brain Imaging of Ischemic Stroke

Published on: June 2, 2023

Optimized System for Cerebral Perfusion Monitoring in the Rat Stroke Model of Intraluminal Middle Cerebral Artery Occlusion
12:15

Optimized System for Cerebral Perfusion Monitoring in the Rat Stroke Model of Intraluminal Middle Cerebral Artery Occlusion

Published on: February 17, 2013

Area of Science:

  • Neurology
  • Radiology
  • Medical Imaging

Background:

  • CT perfusion (CTP) is a valuable tool in acute stroke imaging.
  • CTP abnormalities can be caused by conditions other than acute infarcts.
  • Neurologic diseases can mimic cerebrovascular events, altering brain perfusion.

Purpose of the Study:

  • To analyze and classify pitfalls and artifacts in CTP acquisition and analysis.
  • To guide technicians and radiologists in optimizing CTP examinations.
  • To improve the accuracy of CTP interpretation in acute stroke cases.

Main Methods:

  • Review and classification of CTP imaging data.
  • Analysis of common artifacts and pitfalls in perfusion CT.
  • Identification of factors affecting arterial input function selection.

Main Results:

  • CTP abnormalities are not always indicative of acute infarct.
  • Various neurologic conditions can present as CTP mimics.
  • Technical and analytical pitfalls can lead to misinterpretation of CTP data.

Conclusions:

  • Knowledge of CTP mimics and pitfalls is essential for accurate stroke diagnosis.
  • Proper technique and careful analysis enhance the quality of CTP examinations.
  • Improved understanding aids in differentiating true infarcts from other perfusion alterations.