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Iris melanoma in children: Current approach to management

John P McLaughlin1, Adrian T Fung, Jerry A Shields

  • 1The Ocular Oncology Service, Wills Eye Institute, Thomas Jefferson University, Philadelphia, PA, USA.

Oman Journal of Ophthalmology
|June 18, 2013
PubMed

Insights

Pediatric iris melanoma, though rare, can recur after surgery. This case highlights the need for advanced treatments like Iodine-125 plaque radiotherapy for recurrent eye tumors in young patients.

Area of Science:

  • Ophthalmology
  • Oncology

Background:

  • Iris melanoma typically affects middle-aged Caucasian individuals with light-colored irises.
  • Pediatric iris melanoma is an exceptionally rare occurrence.

Observation:

  • A 15-year-old male presented with a suspected iris nevus, which was monitored over two years.
  • The lesion exhibited significant growth in basal diameter and thickness, necessitating surgical excision.

Findings:

  • Histopathology confirmed spindle cell iris melanoma.
  • The tumor recurred two years post-surgery, involving the anterior chamber angle and causing secondary glaucoma.

Implications:

  • This case underscores the potential for iris melanoma recurrence even after appropriate surgical intervention.
  • Current management strategies for pediatric iris melanoma, including radiotherapy, are crucial for addressing recurrent or advanced disease.

Keywords:
Eyeirismelanomaplaque radiotherapyresectionuvea

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