Related Experiment Video
Updated: May 10, 2026

05:01
Murine Model of Controlled Cortical Impact for the Induction of Traumatic Brain Injury
Published on: August 16, 2019
Maxillofacial injuries and traumatic brain injury--a pilot study
Rama Krsna Rajandram1, Syed Nabil Syed Omar, Muhd Fazly Nizam Rashdi
1Department of Oral and Maxillofacial Surgery, National University of Malaysia, Kuala Lumpur, Malaysia.
Summary
Maxillofacial injuries, including facial fractures, significantly increase the risk of traumatic brain injuries (TBIs). Prompt radiological investigation and follow-up are crucial for all patients with maxillofacial trauma.
Area of Science:
- Trauma surgery
- Neurosurgery
- Emergency medicine
Background:
- Maxillofacial injuries can be linked to traumatic brain injuries (TBIs) due to force transmission through the head and neck.
- The protective or detrimental role of maxillofacial injuries on brain injury remains debated.
- Previous research has not adequately documented the relationship between maxillofacial trauma and TBI.
Purpose of the Study:
- To analyze the incidence and association between maxillofacial injuries and traumatic brain injuries.
- To evaluate patients with maxillofacial injuries in a retrospective cross-sectional study.
Main Methods:
- Retrospective analysis of hospital charts from trauma patients at UKM Medical Centre (November 2010 - November 2011).
- Inclusion and exclusion criteria were applied to a detailed analysis of patient records.
- Focus on patients with and without facial fractures to assess TBI co-occurrence.
Main Results:
- Out of 11,294 trauma patients, 176 had facial fractures and 292 did not.
- Middle face fractures were the most prevalent pattern observed.
- Traumatic brain injury (TBI) was present in 36.7% of maxillofacial injury cases, with a significant association (P < 0.05).
- Patients with facial fractures had a 1.5-fold increased risk of TBI (95% CI 1.197-1.909).
Conclusions:
- Maxillofacial injuries, with or without associated facial fractures, pose a risk for acute or delayed traumatic brain injury.
- Comprehensive radiological investigations are recommended for all patients with maxillofacial injuries.
- Proper observation and follow-up schedules are essential for managing patients with maxillofacial trauma and potential TBI.

