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Related Concept Videos

Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...

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Related Experiment Video

Updated: May 10, 2026

Binocular Dynamic Visual Acuity in Eyeglass-Corrected Myopic Patients
07:06

Binocular Dynamic Visual Acuity in Eyeglass-Corrected Myopic Patients

Published on: March 29, 2022

Ocular biometry in angle closure.

Mohammad Reza Razeghinejad1, Mohammad Banifatemi

  • 1Poostchi Ophthalmology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.

Journal of Ophthalmic & Vision Research
|July 5, 2013
PubMed
Summary
This summary is machine-generated.

Biometric differences were not found between primary angle closure suspects (PACS) and primary angle closure glaucoma (PACG). However, thicker corneas and larger lens-axial length factors predict acute primary angle closure (APAC).

Keywords:
BiometryPachymetryPrimary Angle Closure Glaucoma

Related Experiment Videos

Last Updated: May 10, 2026

Binocular Dynamic Visual Acuity in Eyeglass-Corrected Myopic Patients
07:06

Binocular Dynamic Visual Acuity in Eyeglass-Corrected Myopic Patients

Published on: March 29, 2022

Area of Science:

  • Ophthalmology
  • Biometry
  • Glaucoma Research

Background:

  • Primary angle closure glaucoma (PACG) is a significant cause of vision loss.
  • Understanding ocular biometric parameters is crucial for diagnosing and managing angle closure disease.
  • Differentiating between primary angle closure suspects (PACS), primary angle closure glaucoma (PACG), and acute primary angle closure (APAC) is clinically important.

Purpose of the Study:

  • To compare ocular biometric parameters across PACS, PACG, and APAC.
  • To identify specific biometric factors associated with acute primary angle closure.

Main Methods:

  • A cross-sectional study involving 113 patients (33 PACS, 45 PACG, 35 APAC).
  • Ultrasonic biometry was used to measure central corneal thickness (CCT), axial length (AL), anterior chamber depth (ACD), and lens thickness (LT).
  • Derived parameters including lens-axial length factor (LAF) and corrected ACD (CACD) were calculated; logistic regression and ROC analysis were performed.

Main Results:

  • No significant biometric differences were found between PACS and PACG groups.
  • Eyes with APAC exhibited significantly thicker corneas (CCT), thicker lenses (LT), shallower anterior chamber depth (ACD), shallower corrected ACD (CACD), and larger lens-axial length factors (LAF) compared to other groups.
  • ROC analysis indicated that lower ACD, and larger LT, LAF, and CCT were associated with APAC; LAF and CCT were identified as significant risk factors for APAC.

Conclusions:

  • Ocular biometric parameters do not significantly differ between primary angle closure suspects and primary angle closure glaucoma.
  • Increased lens-axial length factor and central corneal thickness are predictive of acute primary angle closure.
  • These findings highlight specific biometric markers for identifying eyes at risk of acute angle closure events.