Bilateral lineal endotheliitis: case report

Area of Science:

• Ophthalmology
• Virology
• Immunology

Background:

• Herpetic lineal endotheliitis is an inflammatory corneal condition potentially linked to herpes virus infections.
• Endothelial cell response to viral infection can manifest as lineal endotheliitis.
• This condition may involve immune reactions to herpes virus antigens.

Observation:

• A 17-year-old female presented with blurred vision and bilateral corneal edema.
• Examination revealed Descemet folds and linear pigmented precipitates in both corneas.
• The patient exhibited signs consistent with herpetic lineal endotheliitis.

Findings:

• Treatment with topical prednisolone and oral acyclovir resulted in complete resolution of signs and symptoms.
• The patient's condition responded favorably to the combined antiviral and corticosteroid therapy.
• This suggests a significant role for viral infection and inflammation in the pathogenesis.

Implications:

• Prompt diagnosis and treatment with antivirals and steroids are crucial for managing herpetic lineal endotheliitis.
• The condition has a potential for relapse, even without active viral replication.
• Further investigations may be necessary for patients unresponsive to standard treatment.