Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: May 9, 2026

Establishment of a Primary Culture of Patient-derived Soft Tissue Sarcoma
07:55

Establishment of a Primary Culture of Patient-derived Soft Tissue Sarcoma

Published on: April 11, 2018

Cutaneous angiosarcoma: a single-institution experience.

Matthew C Perez1, Tapan A Padhya, Jane L Messina

  • 1Morsani College of Medicine, University of South Florida, Tampa, FL, USA.

Annals of Surgical Oncology
|July 10, 2013
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The National Resident Match Program Arrives in Dermatopathology: 15 Years of Resilient Advocacy by the American Society of Dermatopathology's Fellowship Training Program Directors' Committee.

Journal of cutaneous pathology·2026
Same author

A MAFG~MITF complex drives melanoma phenotype switching and progression.

Nature communications·2026
Same author

Associations Between Pigmentation and the Clinicopathologic and Immune Landscape of Melanoma.

The American Journal of dermatopathology·2026
Same author

Sweat Gland Carcinoma With Neuroendocrine Differentiation (SCAND) Harboring a Novel GATA3 Frameshift Extension Mutation: A Case Study With Protein Structural Modeling.

Journal of cutaneous pathology·2026
Same author

A comparison of hemiarthroplasty with aortograft vs. reverse total shoulder arthroplasty following proximal humeral oncologic resection.

Journal of shoulder and elbow surgery·2026
Same author

Acral Melanoma: Review of Clinical, Histologic, and Molecular Findings.

Surgical pathology clinics·2026
Same journal

Lymph Node Yield and Disease-Free Survival After Neoadjuvant Chemoimmunotherapy for Esophageal Squamous Cell Carcinoma: A Multicenter, Retrospective Cohort Study.

Annals of surgical oncology·2026
Same journal

The Role of Surgery on the Treatment of Primary Pulmonary Sarcomas and Pulmonary Sarcomatoid Carcinoma.

Annals of surgical oncology·2026
Same journal

ASO Visual Abstract: Revisiting the Concept of Nerve-Sparing Radical Hysterectomy: A Proof-of-Concept Prospective Study from a Cervical Cancer Cohort.

Annals of surgical oncology·2026
Same journal

ASO Visual Abstract: Sentinel Node Biopsy in the Neck Management of cN0 Sinonasal Squamous Cell Carcinoma-A Multicenter Pilot Trial on Safety and Feasibility.

Annals of surgical oncology·2026
Same journal

ASO Visual Abstract: High Prevalence of Clinical Understaging in Early Gastric Cancer: An Analysis of the NCDB.

Annals of surgical oncology·2026
Same journal

ASO Author Reflections: Looking Beyond Imaging-Multimodal Response Assessment after Modern Neoadjuvant Therapy for Pancreatic Ductal Adenocarcinoma.

Annals of surgical oncology·2026
See all related articles

Cutaneous angiosarcoma (CAS) survival rates are better than previously thought, particularly for trunk/extremity cases. Smaller tumor size (<5 cm) is linked to improved overall survival in CAS patients.

Area of Science:

  • Oncology
  • Surgical Oncology
  • Dermatopathology

Background:

  • Cutaneous angiosarcoma (CAS) is a rare, aggressive vascular tumor.
  • Historically, 5-year survival rates for CAS range from 10-30%.

Purpose of the Study:

  • To analyze outcomes and prognostic factors for patients with CAS.
  • To compare survival rates across different CAS subtypes and treatment modalities.

Main Methods:

  • Retrospective review of 88 CAS patients treated between 1999-2011.
  • Analysis of demographics, tumor characteristics, treatments (surgery, radiation therapy), and survival outcomes.
  • Multivariate analysis to identify significant prognostic factors.

Main Results:

Related Experiment Videos

Last Updated: May 9, 2026

Establishment of a Primary Culture of Patient-derived Soft Tissue Sarcoma
07:55

Establishment of a Primary Culture of Patient-derived Soft Tissue Sarcoma

Published on: April 11, 2018

  • 5-year overall survival (OS) and recurrence-free survival (RFS) were 35.2% and 32.3%, respectively.
  • Surgery alone showed higher OS (46.9%) and RFS (39.9%) but not statistically significant.
  • CAS on trunk/extremities had the best 5-year OS (64.8%), while head/neck CAS had the worst (21.5%).
  • Tumor size <5 cm was a significant predictor of improved OS.

    • Conclusions:

    • CAS prognosis may be better than historically reported, especially for trunk/extremity and Stewart-Treves types.
    • Surgery alone may offer better outcomes, though not statistically significant in this study.
    • Tumor size is a critical prognostic factor for overall survival in cutaneous angiosarcoma.