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Sweat Gland Carcinoma With Neuroendocrine Differentiation (SCAND) Harboring a Novel GATA3 Frameshift Extension

Myles R McCrary1, Pei-Ling Chen2, Jane L Messina2

  • 1Department of Pathology and Cell Biology, Morsani College of Medicine, University of South Florida, Tampa, Florida, USA.

Journal of Cutaneous Pathology
|March 17, 2026
PubMed
Summary

A rare aggressive sweat-gland carcinoma with neuroendocrine differentiation (SCAND) was identified in an elderly male. Molecular analysis revealed a novel GATA3 mutation, supporting SCAND as a distinct entity with a poor prognosis.

Keywords:
cutaneous adnexal malignancyprimary cutaneous low grade neuroendocrine carcinomasweat gland carcinoma with neuroendocrine differentiation

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