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Updated: May 9, 2026

Doppler Optical Coherence Tomography of Retinal Circulation

Doppler Optical Coherence Tomography of Retinal Circulation

Published on: September 18, 2012

Graphics processing unit accelerated intensity-based optical coherence tomography angiography using differential

Yuuki Watanabe¹, Yuhei Takahashi, Hiroshi Numazawa

¹Yamagata University, Bio-systems Engineering, Graduate School of Science and Engineering, 4-3-16 Johnan, Yonezawa, Yamagata 992-8510, Japan. ywata@yz.yamagata-u.ac.jp

Journal of Biomedical Optics

|July 13, 2013

Summary

This summary is machine-generated.

We developed a new optical coherence tomography (OCT) angiography technique that corrects for bulk tissue motion (BTM) using graphics processing units (GPUs) for real-time imaging.

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Integrated Photoacoustic Ophthalmoscopy and Spectral-domain Optical Coherence Tomography

Integrated Photoacoustic Ophthalmoscopy and Spectral-domain Optical Coherence Tomography

Published on: January 15, 2013

Area of Science:

Ophthalmology
Medical Imaging
Biomedical Engineering

Background:

Optical coherence tomography (OCT) angiography is crucial for visualizing microvasculature.
Bulk tissue motion (BTM) artifacts degrade the quality of OCT angiography images.
Real-time imaging is essential for clinical applications.

Purpose of the Study:

To demonstrate an intensity-based OCT angiography technique with bulk-tissue-motion (BTM) correction.
To accelerate image processing using graphics processing units (GPUs).
To enable real-time display of structural OCT and BTM-corrected OCT angiography images.

Main Methods:

Utilized the squared difference of sequential frames for intensity-based OCT angiography.
Implemented BTM correction by minimizing the sum of pixel values in shifted structural OCT images.
Employed a graphics processing unit (GPU) for accelerated parallel image processing.

Main Results:

Successfully extracted BTM-corrected OCT angiographic images.
Achieved a GPU processing rate exceeding that of a line scan camera (46.9 kHz).
Demonstrated real-time display of both structural OCT and BTM-corrected OCT angiography images.

Conclusions:

The developed intensity-based OCT angiography with BTM correction provides high-quality, motion-artifact-free images.
GPU acceleration significantly enhances processing speed for real-time OCT angiography.
This technique holds promise for improved clinical diagnosis and monitoring in ophthalmology.