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Related Experiment Video

Updated: May 9, 2026

A Wireless, Bidirectional Interface for In Vivo Recording and Stimulation of Neural Activity in Freely Behaving Rats
10:41

A Wireless, Bidirectional Interface for In Vivo Recording and Stimulation of Neural Activity in Freely Behaving Rats

Published on: November 7, 2017

A VLSI Neural Monitoring System With Ultra-Wideband Telemetry for Awake Behaving Subjects.

E Greenwald, M Mollazadeh, C Hu

    IEEE Transactions on Biomedical Circuits and Systems
    |July 16, 2013
    PubMed
    Summary
    This summary is machine-generated.

    We developed a miniature, low-power neural recording system for monitoring brain activity in awake animals. This lightweight device enables long-term, continuous data collection for neuroscience research.

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    Related Experiment Videos

    Last Updated: May 9, 2026

    A Wireless, Bidirectional Interface for In Vivo Recording and Stimulation of Neural Activity in Freely Behaving Rats
    10:41

    A Wireless, Bidirectional Interface for In Vivo Recording and Stimulation of Neural Activity in Freely Behaving Rats

    Published on: November 7, 2017

    Long-term Continuous EEG Monitoring in Small Rodent Models of Human Disease Using the Epoch Wireless Transmitter System
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    Long-term Continuous EEG Monitoring in Small Rodent Models of Human Disease Using the Epoch Wireless Transmitter System

    Published on: July 21, 2015

    Optogenetic Manipulation of Neural Circuits During Monitoring Sleep/wakefulness States in Mice
    08:58

    Optogenetic Manipulation of Neural Circuits During Monitoring Sleep/wakefulness States in Mice

    Published on: June 19, 2019

    Area of Science:

    • Neuroscience
    • Neuroengineering
    • Biomedical Engineering

    Background:

    • Long-term monitoring of neuronal activity is crucial for understanding brain dynamics.
    • Existing systems may be too large or power-intensive for chronic implantation in small animals.

    Purpose of the Study:

    • To develop a miniature, lightweight, and low-power system for multichannel neural recording in awake, behaving animals.
    • To enable fundamental insights into brain dynamics for neuroscience and neuroengineering.

    Main Methods:

    • Integration of two custom very-large-scale integrated (VLSI) chips: a neural interface (0.5 μm CMOS) and an ultra-wideband transmitter (0.5 μm Silicon-on-Sapphire).
    • Amplification, filtering, digitization, and transmission of 16 channels of neural data at 1 Mb/s.
    • System includes VLSI circuits, digital interface, battery, and custom housing; total weight 24g.

    Main Results:

    • The system is compact (24g) and suitable for chronic implantation on small animals.
    • Low power consumption (4.8 mA) allows continuous recording for up to 40 hours on a single charge.
    • Successful experimental benchtop characterization and in vivo multichannel recordings from awake, behaving rats.

    Conclusions:

    • The developed system offers a viable solution for long-term, high-fidelity neural monitoring in freely moving subjects.
    • Its miniature size, low power, and extended recording capability advance neuroscience and neuroengineering research.
    • This technology facilitates deeper understanding of brain function in naturalistic conditions.