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Updated: May 9, 2026

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DNAzyme 10-23 - Based Nanomachines for Nucleic Acid Recognition
Published on: February 9, 2024
A difunctional DNA-AuNP dendrimer coupling DNAzyme with intercalators for femtomolar detection of nucleic acids
Mingdi Xu1, Junyang Zhuang, Xian Chen
1Ministry of Education & Fujian Provincial Key Laboratory of Analysis and Detection of Food Safety, Department of Chemistry, Fuzhou University, Fuzhou 350108, PR China.
Abstract:
A novel difunctional DNA-nanogold (AuNP) dendrimer with a hemin-G-quadruplex was for the first time utilized as the nanotag for the in situ amplified electronic signal for nucleic acid detection by coupling high-efficiency DNAzyme with the intercalated methylene blue (MB).

