Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: May 9, 2026

High Throughput Microfluidic Rapid and Low Cost Prototyping Packaging Methods
07:51

High Throughput Microfluidic Rapid and Low Cost Prototyping Packaging Methods

Published on: December 23, 2013

Fault modeling and functional test methods for digital microfluidic biochips.

Tao Xu, K Chakrabarty

    IEEE Transactions on Biomedical Circuits and Systems
    |July 16, 2013
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Standing on the shoulder of giants: Tubed pedicle radial forearm flap reconstruction for cutis aplasia.

    JPRAS open·2020
    Same author

    Parallel scan-like test and multiple-defect diagnosis for digital microfluidic biochips.

    IEEE transactions on biomedical circuits and systems·2013
    Same author

    Defect-aware high-level synthesis and module placement for microfluidic biochips.

    IEEE transactions on biomedical circuits and systems·2013
    Same author

    Chemotherapy plus radiotherapy versus radiotherapy alone in patients with anaplastic glioma: a systematic review and meta-analysis.

    Journal of cancer research and clinical oncology·2013
    Same author

    Over-expression of VEGF and MMP-9 in residual tumor cells of hepatocellular carcinoma after embolization with lipidol.

    Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban·2013
    Same author

    Comprehensive in vivo RNA-binding site analyses reveal a role of Prp8 in spliceosomal assembly.

    Nucleic acids research·2013

    This study introduces functional testing for microfluidic biochips, ensuring dependable operation in critical applications. The new methods validate core functions like droplet handling and sensing without damaging electrodes.

    Area of Science:

    • Microfluidics
    • Biochip Technology
    • Reliability Engineering

    Background:

    • Dependability is crucial for microfluidic biochips in safety-critical applications like point-of-care diagnostics.
    • Current testing methods for microfluidic biochips are function oblivious, failing to verify operational correctness.
    • Ensuring biochip reliability requires robust testing strategies post-manufacture and during operation.

    Purpose of the Study:

    • To introduce and develop functional testing methods for microfluidic biochips.
    • To address the testing of fundamental biochip operations, including dispensing, transportation, mixing, and splitting.
    • To investigate functional testing for pin-constrained biochips and ensure electrode longevity.

    Main Methods:

    • Developed functional testing protocols for key microfluidic operations.

    More Related Videos

    A Microfluidic Chip for the Versatile Chemical Analysis of Single Cells
    15:41

    A Microfluidic Chip for the Versatile Chemical Analysis of Single Cells

    Published on: October 15, 2013

    Microfluidic Chips Controlled with Elastomeric Microvalve Arrays
    18:11

    Microfluidic Chips Controlled with Elastomeric Microvalve Arrays

    Published on: October 1, 2007

    Related Experiment Videos

    Last Updated: May 9, 2026

    High Throughput Microfluidic Rapid and Low Cost Prototyping Packaging Methods
    07:51

    High Throughput Microfluidic Rapid and Low Cost Prototyping Packaging Methods

    Published on: December 23, 2013

    A Microfluidic Chip for the Versatile Chemical Analysis of Single Cells
    15:41

    A Microfluidic Chip for the Versatile Chemical Analysis of Single Cells

    Published on: October 15, 2013

    Microfluidic Chips Controlled with Elastomeric Microvalve Arrays
    18:11

    Microfluidic Chips Controlled with Elastomeric Microvalve Arrays

    Published on: October 1, 2007

  • Incorporated strategies to avoid long electrode actuation times, preventing degradation.
  • Evaluated functional testing through simulations and experimental validation on a fabricated biochip.
  • Studied the specific challenges of functional testing for pin-constrained biochips.

    • Main Results:

    • Demonstrated the feasibility of functional testing for microfluidic biochips.
    • Validated the effectiveness of the proposed methods for core biochip functions.
    • Confirmed that the testing approach prevents electrode degradation.
    • Experimental results align with simulation predictions for a fabricated biochip.

    Conclusions:

    • Functional testing is essential for ensuring the dependability of microfluidic biochips in critical applications.
    • The proposed methods provide a reliable means to test biochip functionality without compromising device integrity.
    • This work advances the field of microfluidic biochip testing, enabling more trustworthy devices.