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Organic affective psychosis associated with the routine use of non-prescription cold preparations
T M Brown1, R N Golden, D L Evans
1Department of Psychiatry, University of North Carolina, School of Medicine, Chapel Hill 27599.
Abstract:
A patient experienced an organic affective psychosis on three separate occasions after taking recommended doses of non-prescription cold/sinus preparations. The possible underlying pharmacological mechanisms of this clinical reaction lend support to the cholinergic-adrenergic balance hypothesis of affective disorders. Recognition of this acute drug-induced state can lead to appropriate short-term pharmacotherapy and can prevent misdiagnosis of a major affective disorder or schizophrenia.