Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Pediatric Eye Evaluations Preferred Practice Pattern.

Ophthalmology·2022
Same author

Amblyopia Preferred Practice Pattern.

Ophthalmology·2022
Same author

Esotropia and Exotropia Preferred Practice Pattern®.

Ophthalmology·2022
Same author

The Pediatric Optic Neuritis Prospective Outcomes Study: Two-Year Results.

Ophthalmology·2022
Same author

Secondary 12-Month Ocular Outcomes of a Phase 1 Dosing Study of Bevacizumab for Retinopathy of Prematurity.

JAMA ophthalmology·2019
Same author

Practice patterns to decrease myopia progression differ among paediatric ophthalmologists around the world.

The British journal of ophthalmology·2019
Same journal

Laser vision correction (LASIK, PRK, SMILE) with simultaneous accelerated corneal crosslinking.

Current opinion in ophthalmology·2026
Same journal

Traumatic macular hole: observe, operate, or other options.

Current opinion in ophthalmology·2026
Same journal

The evolving role of artificial intelligence in ophthalmology: basic science, translation, and clinical integration.

Current opinion in ophthalmology·2026
Same journal

Editorial: reducing risk for refractive surgery.

Current opinion in ophthalmology·2026
Same journal

Updates on Refractive Surgery: Benefits, Risks, and Costs of Modern Treatment Options.

Current opinion in ophthalmology·2026
Same journal

Corneal Allogeneic Intrastromal Ring Segments for keratoconus - recent evidence and the move to customized and custom shaped CAIRS.

Current opinion in ophthalmology·2026
See all related articles

Related Experiment Video

Updated: May 9, 2026

Dynamic Visual Tests to Identify and Quantify Visual Damage and Repair Following Demyelination in Optic Neuritis Patients
12:23

Dynamic Visual Tests to Identify and Quantify Visual Damage and Repair Following Demyelination in Optic Neuritis Patients

Published on: April 14, 2014

Update in pediatric optic neuritis.

Janine E Collinge1, Derek T Sprunger

  • 1Department of Pediatric Ophthalmology and Adult Strabismus, Indiana University Health, Indianapolis, Indiana, USA. janine.collinge@gmail.com

Current Opinion in Ophthalmology
|July 23, 2013
PubMed
Summary
This summary is machine-generated.

Pediatric optic neuritis differs from adult forms, with new research clarifying its features and links to demyelinating diseases. Corticosteroids are standard treatment, but further trials are needed for optimal management.

More Related Videos

Ocular Therapeutic Delivery and Advanced Tissue Retrieval in Adult Rats
06:30

Ocular Therapeutic Delivery and Advanced Tissue Retrieval in Adult Rats

Published on: May 23, 2025

A Surgical Approach for Optic Nerve Crush in a Rabbit Model
06:15

A Surgical Approach for Optic Nerve Crush in a Rabbit Model

Published on: July 8, 2025

Related Experiment Videos

Last Updated: May 9, 2026

Dynamic Visual Tests to Identify and Quantify Visual Damage and Repair Following Demyelination in Optic Neuritis Patients
12:23

Dynamic Visual Tests to Identify and Quantify Visual Damage and Repair Following Demyelination in Optic Neuritis Patients

Published on: April 14, 2014

Ocular Therapeutic Delivery and Advanced Tissue Retrieval in Adult Rats
06:30

Ocular Therapeutic Delivery and Advanced Tissue Retrieval in Adult Rats

Published on: May 23, 2025

A Surgical Approach for Optic Nerve Crush in a Rabbit Model
06:15

A Surgical Approach for Optic Nerve Crush in a Rabbit Model

Published on: July 8, 2025

Area of Science:

  • Ophthalmology
  • Neurology
  • Pediatrics

Background:

  • Pediatric optic neuritis presents distinct features compared to adult cases.
  • Early recognition is crucial for patient evaluation and prognosis.
  • Understanding its association with progressive demyelinating disorders is vital.

Purpose of the Study:

  • To review current understanding of pediatric optic neuritis.
  • To highlight recent advancements in diagnosis and management.
  • To identify knowledge gaps and future research directions.

Main Methods:

  • Review of recent studies on pediatric optic neuritis.
  • Analysis of demographic and presenting features.
  • Evaluation of emerging biomarkers and optical coherence tomography (OCT) utility.

Main Results:

  • Expanded knowledge of pediatric optic neuritis demographics and presentation.
  • Biomarkers and OCT show potential prognostic value.
  • Better understanding of risk factors for progression to systemic demyelinating processes like multiple sclerosis.
  • Corticosteroids remain the primary treatment; immunosuppressive therapies show success in refractory cases.

Conclusions:

  • Comprehensive understanding and optimal management of pediatric optic neuritis are still developing.
  • A randomized clinical trial is needed to advance knowledge and improve patient outcomes.