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Simultaneous cerebral arterial and venous thrombosis
D Nagaraja1, A B Taly, S K Shankar
1Department of Neurology, National Institute of Mental Health and Neuro Sciences, Bangalore.
Insights
Simultaneous arterial and venous stroke is rare. Autopsy revealed co-existing arterial and venous infarctions, alongside arterial and venous thrombosis in three patients, highlighting potential contributing factors.
Area of Science:
- Neurology
- Pathology
- Vascular Medicine
Background:
- Cerebral arterial and venous thrombosis occurring simultaneously in the same individual is an exceptionally rare clinical presentation.
- Understanding the pathogenesis of combined arterial and venous cerebrovascular events is crucial for diagnosis and treatment.
Observation:
- This report details three patients who presented with stroke and, upon autopsy, were found to have co-existing arterial and venous infarctions.
- These cases demonstrated major arterial occlusions (vertebral and internal carotid arteries) coupled with thrombosis of dural sinuses and cortical veins.
Findings:
- The study highlights the co-occurrence of arterial occlusion and cerebral venous sinus thrombosis in the same patients.
- Potential contributing factors to this rare condition, including infarcted brain tissue, haemorrheological factors, and alcohol consumption, are discussed.
Implications:
- This case series expands the understanding of rare cerebrovascular pathologies involving both arterial and venous systems.
- Further research into the interplay of vascular occlusion, brain infarction, and systemic factors may elucidate the mechanisms behind these complex stroke presentations.
Abstract:
Simultaneous thrombotic occlusion of cerebral arterial and venous systems in the same individual is rare. Three patients of stroke in whom autopsy revealed co-existing arterial and venous infarctions, major arterial occlusion (vertebral 1, internal carotid 1) and dural sinus and cortical vein thrombosis are reported. Role of infarcted brain, haemorrheological factors and alcohol in the pathogenesis of this rare event is highlighted.