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Updated: May 9, 2026
07:25
A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer
Published on: March 6, 2018
[Vitamin D and prostate cancer]
Goran Marusić1, Dimitrije Jeremić, Sasa Vojinov
1Klinicki centar Vojvodine, Klinika za urologiju, Medicinski fakultet Univerziteta u Novom Sadu, Novi Sad. gmarusic@neobee.net
Medicinski Pregled
|July 30, 2013
Summary
Vitamin D may inhibit prostate cancer cell growth and promote cell death. Further research is needed to fully understand vitamin D
Area of Science:
- Endocrinology and Oncology
- Molecular Biology
Context:
- Prostate cancer is a significant global health concern, representing the second most common malignancy in men.
- The long cancerogenesis period and available biomarkers make prostate cancer a suitable target for preventive strategies.
Purpose:
- To explore the potential anti-proliferative and pro-apoptotic roles of vitamin D in prostate cancer.
- To investigate the impact of genetic variations in vitamin D metabolism and related receptors on prostate cancer development.
Summary:
- Emerging evidence suggests vitamin D possesses anti-proliferative and pro-apoptotic properties relevant to prostate cancer cells.
- Alterations in vitamin D metabolism, including genetic factors affecting vitamin D and androgen receptors, are implicated in prostate cancer.
- In vitro and in vivo studies support vitamin D's role in modulating cancer cell behavior.
Impact:
- Understanding vitamin D's mechanisms in prostate cancer could lead to novel preventive and therapeutic approaches.
- Further research is crucial to elucidate the complex interplay between vitamin D, its metabolism, and prostate cancer pathogenesis.
- Genetic insights may identify individuals at higher risk or those who could benefit from vitamin D-related interventions.
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