Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Esophageal Achalasia01:27

Esophageal Achalasia

Esophageal achalasia is a chronic neurogenic disorder characterized by impaired relaxation of the lower esophageal sphincter (LES) and absent or ineffective peristalsis in the distal esophagus. This leads to a functional obstruction without a physical blockage, despite significant disruption of esophageal motility.EtiologyAchalasia is caused by degeneration of the myenteric (Auerbach's) plexus, specifically the loss of inhibitory ganglion cells that produce vasoactive intestinal peptide (VIP)...
Esophageal Strictures-I: Introduction01:30

Esophageal Strictures-I: Introduction

Esophageal strictures involve abnormal narrowing or tightening of the esophagus. They vary in length and severity, ranging from mild constriction to complete obstruction, and are classified as benign (noncancerous) or malignant (cancerous).
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
Gastroesophageal Reflux Disease01:25

Gastroesophageal Reflux Disease

Gastroesophageal reflux disease (GERD) is the backward flow of stomach contents (acid, pepsin, or bile) into the esophagus, causing mucosal inflammation known as esophagitis. It results from failure of antireflux mechanisms, mainly the lower esophageal sphincter (LES), influenced by mechanical and physiological factors.Etiology and Risk FactorsGERD develops when LES function is weakened or when intra-abdominal pressure increases. Risk factors include aging, obesity, and sliding hiatal hernia,...
Barrett Esophagus-II: Clinical Manifestations and Management01:21

Barrett Esophagus-II: Clinical Manifestations and Management

Individuals with Barrett's esophagus are often asymptomatic, but they may experience symptoms commonly associated with GERD, such as heartburn and acid regurgitation. Additional symptoms can include difficulty swallowing, chest pain, unintentional weight loss, blood in the stool (which may appear black, tarry, or bloody), and episodes of vomiting.
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure entails...
Asthma I: Introduction01:28

Asthma I: Introduction

Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...
Barrett Esophagus-I: Introduction01:21

Barrett Esophagus-I: Introduction

Barrett's esophagus is a medical condition where the esophageal mucosa is significantly damaged by stomach acid or other digestive fluids, often due to long-term exposure associated with gastroesophageal reflux disease (GERD). In GERD, a weakened or abnormally relaxed lower esophageal sphincter allows stomach acid to flow persistently into the esophagus.
This constant acid exposure transforms the esophagus's pink mucosal lining (stratified squamous epithelium) into a type of lining more similar...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Association of bowel urgency, disease activity and disability in patients with inflammatory bowel disease: A cross-sectional study from the GETAID.

Clinics and research in hepatology and gastroenterology·2026
Same author

Follow-up, cancer risk and mortality in Peutz-Jeghers syndrome: Data from the PRED-IdF network.

European journal of human genetics : EJHG·2026
Same author

European Society for the Study of Coeliac Disease (ESsCD) 2025 Updated Guidelines on the Diagnosis and Management of Coeliac Disease in Adults. Part 2: Management, Follow-Up, and Complex Disease Courses.

United European gastroenterology journal·2026
Same author

Association between physical activity with disease activity and functional disability in patients with inflammatory bowel disease.

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·2026
Same author

Diet and clinical remission in patients with inflammatory bowel disease: A multicenter cross-sectional study.

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·2025
Same author

[Tapia syndrome following orotracheal intubation in intensive care unit].

La Revue de medecine interne·2025
Same journal

Artificial Intelligence in medical research and publishing: progress, risks, and future perspectives.

Presse medicale (Paris, France : 1983)·2026
Same journal

Ethical, legal, and regulatory challenges in AI-based healthcare tools.

Presse medicale (Paris, France : 1983)·2026
Same journal

Decision-making for clinicians.

Presse medicale (Paris, France : 1983)·2026
Same journal

Beyond one-size-fits-all: Personalising health communication to drive real behaviour change.

Presse medicale (Paris, France : 1983)·2026
Same journal

Metacognition and post-decisional processing in clinical decision-making.

Presse medicale (Paris, France : 1983)·2026
Same journal

Fast-and-frugal decision trees for clinicians.

Presse medicale (Paris, France : 1983)·2026
See all related articles

Related Experiment Video

Updated: May 9, 2026

Three-Dimensional Cell Culture Models to Investigate the Epithelial Barrier in Eosinophilic Esophagitis
03:23

Three-Dimensional Cell Culture Models to Investigate the Epithelial Barrier in Eosinophilic Esophagitis

Published on: May 10, 2024

[Eosinophilic esophagitis].

Elodie Saillen1, Christophe Cellier2, Anne-Laure Naneix3

  • 1Assistance publique-Hôpitaux de Paris, université Paris Descartes, Paris Sorbonne Cité, hôpital Européen Georges-Pompidou, service de médecine interne, 20, rue Leblanc, 75015 Paris, France.

Presse Medicale (Paris, France : 1983)
|July 30, 2013
PubMed
Summary
This summary is machine-generated.

Eosinophilic esophagitis is a key cause of dysphagia in young men, often linked to allergies. Diagnosis requires confirming unresponsiveness to proton pump inhibitors, with topical corticoids as the primary treatment.

More Related Videos

Using the Endoscope for Endobronchial Ultrasound in the Esophagus
04:35

Using the Endoscope for Endobronchial Ultrasound in the Esophagus

Published on: November 21, 2023

Development of Compendium for Esophageal Squamous Cell Carcinoma
03:36

Development of Compendium for Esophageal Squamous Cell Carcinoma

Published on: April 12, 2024

Related Experiment Videos

Last Updated: May 9, 2026

Three-Dimensional Cell Culture Models to Investigate the Epithelial Barrier in Eosinophilic Esophagitis
03:23

Three-Dimensional Cell Culture Models to Investigate the Epithelial Barrier in Eosinophilic Esophagitis

Published on: May 10, 2024

Using the Endoscope for Endobronchial Ultrasound in the Esophagus
04:35

Using the Endoscope for Endobronchial Ultrasound in the Esophagus

Published on: November 21, 2023

Development of Compendium for Esophageal Squamous Cell Carcinoma
03:36

Development of Compendium for Esophageal Squamous Cell Carcinoma

Published on: April 12, 2024

Area of Science:

  • Gastroenterology
  • Immunology
  • Allergy

Context:

  • Eosinophilic esophagitis is a primary cause of dysphagia and food impaction in young adult males.
  • This condition is characterized by esophageal inflammation and is frequently associated with allergies and atopy.
  • It predominantly affects Caucasian males with a 3:1 male-to-female ratio.

Purpose:

  • To outline the diagnostic criteria and recommended initial treatment for eosinophilic esophagitis.
  • To highlight the association between eosinophilic esophagitis, allergies, and atopy.
  • To emphasize the importance of unresponsiveness to proton pump inhibitors for diagnosis.

Summary:

  • Eosinophilic esophagitis is an esophageal-specific inflammatory condition linked to allergies.
  • Diagnosis involves clinical, histological confirmation, and demonstrating unresponsiveness to proton pump inhibitors.
  • The recommended first-line therapy is topical corticosteroids.

Impact:

  • Provides a concise overview of eosinophilic esophagitis for clinicians and researchers.
  • Highlights the diagnostic challenges and emphasizes the role of allergy in the condition.
  • Establishes topical corticoids as the primary therapeutic strategy, guiding clinical practice.