Related Experiment Video
Updated: May 9, 2026

Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure
Published on: February 8, 2022
Ventricular septal dysfunction after surgical closure of multiple ventricular septal defects
Hironori Matsuhisa1, Naoki Yoshimura, Tomonori Higuma
1First Department of Surgery, University of Toyama, Graduate School of Medicine, Toyama, Japan. matsuhisa_kch@hp.pref.hyogo.jp
Postoperative ventricular septal function is reduced in children with multiple ventricular septal defects, particularly when large patches are used for closure. Minimizing patch material may preserve function.
Area of Science:
- Pediatric Cardiology
- Cardiac Surgery
- Echocardiography
Background:
- Assessed global and regional ventricular septal function in children with postoperative multiple ventricular septal defects (VSDs).
- Utilized conventional echocardiography and 2D speckle tracking imaging (STI).
Purpose of the Study:
- To evaluate the impact of surgical closure techniques on ventricular septal function in children with multiple VSDs.
- To correlate patch material usage with postoperative cardiac function.
Main Methods:
- Studied 36 children (16 with postoperative multiple VSDs, 20 controls).
- Analyzed 60 VSD closures using patch, sandwich, or direct techniques.
- Applied STI to three short-axis echocardiographic views.
Main Results:
- Total patch area correlated with reduced ejection fraction and Tei index.
- Global septal function (displacement and strain) was significantly lower in the VSD group.
- Patch and sandwich techniques showed reduced regional function compared to intact segments; direct closure had no significant regional depression.
Conclusions:
- Postoperative ventricular and septal functions are significantly reduced in children with multiple VSDs, especially with complex disease and large prosthetic material use.
- Minimizing patch material may help preserve postoperative ventricular function.
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