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Related Experiment Video

Updated: May 9, 2026

Standardized Hemorrhagic Shock Induction Guided by Cerebral Oximetry and Extended Hemodynamic Monitoring in Pigs
07:51

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Haemorrhagic shock, therapeutic management.

J-S David1, C Spann, G Marcotte

  • 1Department of Anaesthesia and Intensive Care, Lyon Sud Hospital, Hospices Civils de Lyon, 69495 Pierre-Bénite cedex, France. jean-stephane.david@chu-lyon.fr

Annales Francaises D'Anesthesie Et De Reanimation
|July 31, 2013
PubMed
Summary

This study outlines a "Play and Run" prehospital strategy for managing traumatic hemorrhagic shock, focusing on early bleeding control and addressing factors like hypothermia, acidosis, and coagulopathy. The goal is to achieve hemostasis using Damage Control Resuscitation principles, including permissive hypotension.

Keywords:
Damage controlHaemorrhageHypotension permissiveHémorragiePermissive hypotensionTrauma

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Last Updated: May 9, 2026

Standardized Hemorrhagic Shock Induction Guided by Cerebral Oximetry and Extended Hemodynamic Monitoring in Pigs
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Published on: May 21, 2019

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Fixed Volume or Fixed Pressure: A Murine Model of Hemorrhagic Shock
16:31

Fixed Volume or Fixed Pressure: A Murine Model of Hemorrhagic Shock

Published on: June 6, 2011

Area of Science:

  • Emergency Medicine
  • Trauma Surgery
  • Critical Care

Background:

  • Post-traumatic hemorrhagic shock management requires a coordinated prehospital and in-hospital approach.
  • Effective treatment necessitates addressing both bleeding sources and physiological derangements.

Purpose of the Study:

  • To describe a comprehensive strategy for managing patients in post-traumatic hemorrhagic shock.
  • To highlight the integration of prehospital interventions with in-hospital Damage Control Resuscitation.

Main Methods:

  • Implementing a "Play and Run" prehospital strategy for rapid transport to a specialized trauma center.
  • Utilizing early hemorrhage control measures: tourniquets, pelvic binders, and hemostatic dressings.
  • Applying Damage Control Resuscitation principles, including permissive hypotension and correction of hypothermia, acidosis, and coagulopathy.

Main Results:

  • Early application of tourniquets, pelvic binders, and hemostatic dressings is crucial for bleeding control.
  • Addressing hypothermia, acidosis, and coagulopathy alongside resuscitation is vital.
  • Maintaining a target systolic blood pressure of 90 mmHg until hemostasis is achieved is a key objective.

Conclusions:

  • A multidisciplinary approach integrating prehospital care with Damage Control Resuscitation improves outcomes in hemorrhagic shock.
  • Timely surgical or radiological intervention is essential for definitive hemorrhage control.
  • Managing the "triad of death" (hypothermia, acidosis, coagulopathy) is fundamental to successful resuscitation.