Related Experiment Video
Updated: May 9, 2026

Standardized Hemorrhagic Shock Induction Guided by Cerebral Oximetry and Extended Hemodynamic Monitoring in Pigs
Published on: May 21, 2019
Haemorrhagic shock, therapeutic management
J-S David1, C Spann, G Marcotte
1Department of Anaesthesia and Intensive Care, Lyon Sud Hospital, Hospices Civils de Lyon, 69495 Pierre-Bénite cedex, France. jean-stephane.david@chu-lyon.fr
This study outlines a "Play and Run" prehospital strategy for managing traumatic hemorrhagic shock, focusing on early bleeding control and addressing factors like hypothermia, acidosis, and coagulopathy. The goal is to achieve hemostasis using Damage Control Resuscitation principles, including permissive hypotension.
Area of Science:
- Emergency Medicine
- Trauma Surgery
- Critical Care
Background:
- Post-traumatic hemorrhagic shock management requires a coordinated prehospital and in-hospital approach.
- Effective treatment necessitates addressing both bleeding sources and physiological derangements.
Purpose of the Study:
- To describe a comprehensive strategy for managing patients in post-traumatic hemorrhagic shock.
- To highlight the integration of prehospital interventions with in-hospital Damage Control Resuscitation.
Main Methods:
- Implementing a "Play and Run" prehospital strategy for rapid transport to a specialized trauma center.
- Utilizing early hemorrhage control measures: tourniquets, pelvic binders, and hemostatic dressings.
- Applying Damage Control Resuscitation principles, including permissive hypotension and correction of hypothermia, acidosis, and coagulopathy.
Main Results:
- Early application of tourniquets, pelvic binders, and hemostatic dressings is crucial for bleeding control.
- Addressing hypothermia, acidosis, and coagulopathy alongside resuscitation is vital.
- Maintaining a target systolic blood pressure of 90 mmHg until hemostasis is achieved is a key objective.
Conclusions:
- A multidisciplinary approach integrating prehospital care with Damage Control Resuscitation improves outcomes in hemorrhagic shock.
- Timely surgical or radiological intervention is essential for definitive hemorrhage control.
- Managing the "triad of death" (hypothermia, acidosis, coagulopathy) is fundamental to successful resuscitation.
Related Concept Videos
Blood Pressure Imbalances and Circulatory Shock
Blood Pressure: Hypertension and Hypotension
Normal blood pressure is 120/80 mm Hg. Elevated blood pressure is 120-129/under 80 mm Hg. Hypertension, warranting treatment at 130/80 mm Hg, is often asymptomatic and can lead to severe cardiovascular events, aneurysms, peripheral arterial disease, chronic renal disease, or cardiac...
Esophageal Varices-II: Clinical Features and Management
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol abuse, or...
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care
Venous Thrombosis III: Interprofessional Care
Venous Thrombosis IV: Nursing Management
Hemorrhagic Stroke ll: Pathophysiology

