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Related Concept Videos

Multiple Sclerosis l: Introduction01:19

Multiple Sclerosis l: Introduction

Multiple sclerosis is a chronic autoimmune disease of the central nervous system (CNS) that affects the brain, spinal cord, and optic nerves. It is an inflammatory demyelinating disorder and a leading cause of neurological disability in young adults.EpidemiologyMS commonly begins between 20 and 40 years of age and is twice as common in women. Its exact cause remains unclear, but genetic susceptibility contributes, with higher risk in first-degree relatives and identical twins. A greater...

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The Multiple Sclerosis Performance Test (MSPT): An iPad-Based Disability Assessment Tool
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Published on: June 30, 2014

Objectively quantified physical activity in persons with multiple sclerosis.

Rachel E Klaren1, Robert W Motl1, Deirdre Dlugonski1

  • 1Department of Kinesiology and Community Health, University of Illinois at Urbana-Champaign, Urbana, IL.

Archives of Physical Medicine and Rehabilitation
|August 3, 2013
PubMed
Summary
This summary is machine-generated.

People with multiple sclerosis (MS) engage in significantly less moderate-to-vigorous physical activity (MVPA) daily compared to healthy controls. Objective accelerometry data show a small percentage of MS patients meet public health guidelines for physical activity.

Keywords:
ANCOVAAccelerometryCIMSMVPAMotor activityMultiple sclerosisPDDSPatient-Determined Disease StepsQOLRehabilitationanalysis of covarianceconfidence intervalmoderate-to-vigorous physical activitymultiple sclerosisquality of life

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Area of Science:

  • Neurology
  • Rehabilitation Medicine
  • Exercise Science

Background:

  • Multiple Sclerosis (MS) is a chronic neurological disease.
  • Physical activity is crucial for managing MS symptoms and overall health.
  • Objective measurement of physical activity in MS populations is essential.

Purpose of the Study:

  • To quantify moderate-to-vigorous physical activity (MVPA) levels in a large cohort of individuals with MS.
  • To compare MVPA levels and adherence to public health guidelines between individuals with MS and healthy controls.
  • To identify factors influencing MVPA in persons with MS.

Main Methods:

  • Secondary analysis of a combined dataset from 13 studies (2005-2013).
  • Inclusion of 800 individuals with MS and 137 healthy controls.
  • Objective measurement of physical activity using accelerometry.

Main Results:

  • Individuals with MS accumulated 13.1 fewer minutes of MVPA per day compared to controls, a statistically significant difference (P<.001).
  • Only 20% of individuals with MS met public health guidelines for MVPA, versus 47% of controls (P<.001).
  • MVPA in the MS group varied significantly with education, employment, clinical course, disease duration, and disability status.

Conclusions:

  • Objective data from a large sample indicate that a low proportion of individuals with MS achieve recommended daily MVPA.
  • Significant disparities in physical activity levels exist between persons with MS and healthy controls.
  • Further research and interventions are needed to promote physical activity in the MS population.