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An Oligonucleotide-based Tandem RNA Isolation Procedure to Recover Eukaryotic mRNA-Protein Complexes
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A multidimensional platform for the purification of non-coding RNA species

Yok Hian Chionh1, Chia-Hua Ho, Dumnoensun Pruksakorn

  • 1Singapore-MIT Alliance for Research and Technology, Infectious Disease Interdisciplinary Research Group, Campus for Research Excellence and Technological Enterprise, Singapore 138602, Department of Microbiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Department of Biological Engineering and Center for Environmental Health Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA, Applied Biological Science Program, Chulabhorn Graduate Institute, Bangkok 10210, Thailand, Division of Molecular Genetics & Cell Biology, School of Biological Sciences, Nanyang Technological University, Singapore 637551, Immunology Programme, Life Science Institute, Centre for Life Science, Singapore 117456 and Novartis Institute for Tropical Disease, Singapore 138670.

Nucleic Acids Research
|August 3, 2013
PubMed
Summary

Researchers developed a new multidimensional chromatography platform for direct analysis of all non-coding RNA (ncRNA) species. This method enables comprehensive RNA epigenetics and novel ncRNA discovery in various biological samples.

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