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Updated: May 9, 2026

Applications of Liquid-Chromatography Tandem Mass Spectrometry in Natural Products Research: Tropane Alkaloids as a Case Study
Published on: March 8, 2024
Two new alkaloids from Corydalis humosa
Xiao-Ke Zheng1, Dan-Dan Li, Hui Yan
1a School of Pharmacy, Henan University of Traditional Chinese Medicine , Zhengzhou , 450046 , China.
Abstract:
Two new alkaloids, named 1,1-dimethyl-6-methoxy-7-hydroxyl-1,2,3,4-tetrahydroisoquinoline (1) and (1R)-(4-hydroxybenzyl)-7-hydroxyl-8-O-β-d-glucopyranosyl-1,2,3,4-tetrahydroisoquinoline (2), together with 11 known compounds (3-13), were isolated from the tubers of Corydalis humosa. Their structures were elucidated on the basis of their spectroscopic and chemical evidence.
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