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Updated: May 9, 2026

Three Different Protocols of Corneal Collagen Crosslinking in Keratoconus: Conventional, Accelerated and Iontophoresis
Published on: November 12, 2015
Toric implantable collamer lens for keratoconus.
Mathew Kurian Kummelil1, M S Hemamalini, Ridhima Bhagali
1Cataract and Refractive Lens Surgery Services, Narayana Nethralaya, Post-Graduate Institute of Ophthalmology, Bangalore, Karnataka, India.
Toric posterior chamber phakic intraocular lenses (PC pIOLs) offer a safe and effective solution for vision correction in keratoconus patients. While improving refractive errors, higher-order aberrations may still affect overall visual quality.
Area of Science:
- Ophthalmology
- Corneal Surgery
- Refractive Surgery
Background:
- Keratoconus is a progressive corneal thinning causing myopia and irregular astigmatism, significantly impacting vision quality.
- Patients with keratoconus often experience visual disturbances like diplopia, halos, and ghost images.
- Standard treatments may be unsuitable for some keratoconus patients, necessitating alternative interventions.
Purpose of the Study:
- To evaluate the safety and efficacy of toric posterior chamber phakic intraocular lenses (PC pIOLs) for refractive error correction in keratoconus patients.
- To assess the outcomes of PC pIOL implantation, alone or combined with other procedures, in managing keratoconus-associated visual impairments.
Main Methods:
- The study involved implanting toric posterior chamber phakic intraocular lenses (PC pIOLs) in keratoconus patients unsuitable for other procedures.
- Procedures were performed off-label with specific patient informed consent.
- Data from several reports were aggregated to assess safety and efficacy.
Main Results:
- Reports indicate that toric PC pIOL implantation is a safe procedure for keratoconus patients.
- The efficacy of PC pIOLs in correcting refractive errors associated with keratoconus is supported by available data.
- Corneal higher-order aberrations remain a factor influencing the final visual quality post-procedure.
Conclusions:
- Toric PC pIOLs represent a viable surgical option for keratoconus patients with limited treatment alternatives.
- The procedure demonstrates safety and efficacy in addressing refractive errors.
- Further consideration of corneal higher-order aberrations is necessary for optimizing visual outcomes in these patients.
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