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Larynx

Larynx

The human larynx, often referred to as the voice box, is an intricate organ located in the neck. It serves as a pathway for air to enter the lungs during respiration and is an essential component of voice production.
Anatomy of the Larynx
The larynx consists of various components, including cartilage, muscles, and vocal cords. Its structure includes three large unpaired cartilages—the thyroid, cricoid, and epiglottis—and three smaller paired cartilages—the arytenoids, corniculates, and...

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...

Esophageal Achalasia

Esophageal Achalasia

Esophageal achalasia is a chronic neurogenic disorder characterized by impaired relaxation of the lower esophageal sphincter (LES) and absent or ineffective peristalsis in the distal esophagus. This leads to a functional obstruction without a physical blockage, despite significant disruption of esophageal motility.EtiologyAchalasia is caused by degeneration of the myenteric (Auerbach's) plexus, specifically the loss of inhibitory ganglion cells that produce vasoactive intestinal peptide (VIP)...

Barrett Esophagus-II: Clinical Manifestations and Management

Barrett Esophagus-II: Clinical Manifestations and Management

Individuals with Barrett's esophagus are often asymptomatic, but they may experience symptoms commonly associated with GERD, such as heartburn and acid regurgitation. Additional symptoms can include difficulty swallowing, chest pain, unintentional weight loss, blood in the stool (which may appear black, tarry, or bloody), and episodes of vomiting.
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure entails...

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Related Experiment Video

Updated: May 9, 2026

The Flexible Rhino-Laryngoscope for Awake Nasotracheal Intubation

The Flexible Rhino-Laryngoscope for Awake Nasotracheal Intubation

Published on: August 2, 2024

Laryngeal chondrosarcoma.

Evelyn M Potochny¹, Aaron R Huber

¹Naval Medical Center San Diego, San Diego, CA, USA, evelyn.potochny@med.navy.mil.

Head and Neck Pathology

|August 10, 2013

Summary

This summary is machine-generated.

Laryngeal chondrosarcoma, a rare cartilage tumor, typically progresses slowly. Conservative surgery is recommended for this cricoid cartilage tumor, even with high-grade histology.

Related Experiment Videos

Last Updated: May 9, 2026

The Flexible Rhino-Laryngoscope for Awake Nasotracheal Intubation

The Flexible Rhino-Laryngoscope for Awake Nasotracheal Intubation

Published on: August 2, 2024

Area of Science:

Otolaryngology
Surgical Oncology
Pathology

Background:

Laryngeal chondrosarcoma is a rare neoplasm originating from cartilage within the larynx.
Diagnosis requires integrating clinical presentation, histological examination, and radiographic findings.
Despite histology grade, laryngeal chondrosarcoma often exhibits indolent behavior with low metastatic potential.

Observation:

A case of laryngeal chondrosarcoma originating in the cricoid cartilage is presented.
The patient experienced hoarseness, dysphagia, and odynophagia.
Head and neck computed tomography (CT) scans suggested the diagnosis.

Findings:

The laryngeal chondrosarcoma demonstrated a relatively indolent progression.
Conservative surgical excision with negative margins is the recommended treatment approach.
The patient underwent a hemicricoidectomy for tumor removal.

Implications:

This case highlights the importance of considering chondrosarcoma in laryngeal masses.
Conservative management is often effective, preserving laryngeal function.
Accurate diagnosis and tailored surgical intervention are crucial for favorable outcomes in laryngeal chondrosarcoma.