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[Local anesthetic mixtures in various regional anesthesia procedures]
C Schnorr1, T Menges, G Hempelmann
1Abteilung Anästhesiologie und Operative Intensivmedizin am Klinikum der Justus-Liebig-Universität Giessen.
Anasthesie, Intensivtherapie, Notfallmedizin
|June 1, 1990
Summary
Local anesthetic mixtures are commonly used in regional anesthesia, despite controversy. However, their unpredictable effects suggest cautious use in exceptional cases only.
Area of Science:
- Anesthesiology
- Pharmacology
Background:
- The use of local anesthetic mixtures in regional anesthesia is a subject of ongoing debate.
- Understanding anesthesiologists' opinions and practices regarding these mixtures is crucial.
Purpose of the Study:
- To investigate anesthesiologists' opinions on the use of local anesthetic mixtures in regional anesthesia.
- To identify common mixtures, applications, and reasons for use or non-use.
Main Methods:
- A questionnaire-based survey was conducted among 131 anesthesiologists.
- Data collected included frequency of regional anesthesia procedures, use of mixtures, types of mixtures, and reasons for use/rejection.
Main Results:
- 70.2% of respondents use local anesthetic mixtures, commonly in brachial plexus blocks, spinal, and epidural anesthesia.
- Bupivacaine with prilocaine or mepivacaine were the most frequent mixtures, often chosen for rapid onset and prolonged duration.
- Reasons for use included achieving desired effects within safe dosage limits and perceived lower toxicity.
- Rejection of mixtures was primarily due to unpredictable effects and potential for local anesthetic interactions.
Conclusions:
- Local anesthetic mixtures are frequently employed in regional anesthesia practices.
- Despite common use, concerns regarding unpredictable effects and interactions persist.
- The study concludes that mixtures of local anesthetics should be reserved for exceptional circumstances.