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Detection of Low Copy Number Integrated Viral DNA Formed by In Vitro Hepatitis B Infection
11:14

Detection of Low Copy Number Integrated Viral DNA Formed by In Vitro Hepatitis B Infection

Published on: November 7, 2018

An analysis of the molecular evolution of hepatitis B viral genotypes A/B/D using a Bayesian evolutionary method

Guangyu Xu, Chengguo Wei, Yuqi Guo

    Virology Journal
    |August 14, 2013
    PubMed
    Summary

    Hepatitis B virus (HBV) evolution occurred rapidly, with core protein gene mutation rates estimated at over one substitution per site annually. Bayesian analysis revealed the most recent common ancestor (TMRCA) for genotypes A, B, and D emerged centuries ago, with significant genetic diversity arising early.

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