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Updated: May 8, 2026

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Cellular Lipid Extraction for Targeted Stable Isotope Dilution Liquid Chromatography-Mass Spectrometry Analysis
Published on: November 17, 2011
Improved chiral SFC screening for analytical method development
Wes Schafer1, Tilak Chandrasekaran, Zainab Pirzada
1Analytical Chemistry, Merck Research Laboratories, Rahway, New Jersey.
Chirality
|August 16, 2013
Abstract:
In this study we describe the evaluation of a recently developed supercritical fluid chromatography (SFC) instrument for automated chiral SFC method development. The greatly improved gradient dwell volume and liquid flow control of the new instrument in combination with the use of shorter columns containing smaller stationary phase particles affords chiral SFC method development that is faster and more universal than previous systems.

