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Related Experiment Video

Updated: May 8, 2026

Non-invasive 3D-Visualization with Sub-micron Resolution Using Synchrotron-X-ray-tomography

Non-invasive 3D-Visualization with Sub-micron Resolution Using Synchrotron-X-ray-tomography

Published on: May 27, 2008

Three-dimensional phase-contrast X-ray microtomography with scanning-imaging X-ray microscope optics.

Akihisa Takeuchi¹, Kentaro Uesugi, Yoshio Suzuki

¹Research and Utilization Division, Japan Synchrotron Radiation Research Institute, 1-1-1 Kouto, Sayo, Sayo-gun, Hyogo 679-5198, Japan. take@spring8.or.jp

Journal of Synchrotron Radiation

|August 20, 2013

Summary

A novel three-dimensional (3D) X-ray tomographic micro-imaging system, the scanning-imaging X-ray microscope (SIXM), has been developed. This system enables quantitative 3D imaging with flexible contrast modes after data acquisition.

Keywords:

X-ray microscopy differential phase contrast tomography

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Last Updated: May 8, 2026

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Published on: May 27, 2008

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3D Imaging of Soft-Tissue Samples using an X-ray Specific Staining Method and Nanoscopic Computed Tomography

3D Imaging of Soft-Tissue Samples using an X-ray Specific Staining Method and Nanoscopic Computed Tomography

Published on: October 24, 2019

Area of Science:

Microscopy
X-ray imaging
Tomography

Background:

Developing advanced 3D micro-imaging systems is crucial for detailed structural analysis.
Existing methods may have limitations in resolution, contrast flexibility, or quantitative accuracy.

Purpose of the Study:

To develop and demonstrate a novel three-dimensional (3D) X-ray tomographic micro-imaging system.
To evaluate the feasibility of the scanning-imaging X-ray microscope (SIXM) for quantitative 3D imaging.

Main Methods:

The system utilizes scanning-imaging X-ray microscope (SIXM) optics, a hybrid of scanning and imaging microscopy.
A line-focused X-ray beam illuminates the object, and 1D line-profile data are acquired.
Tomographic scanning combined with SIXM enables quantitative 3D reconstruction.

Main Results:

The SIXM system successfully acquired 2D image data through object scanning with a line focus.
Imaging modes like phase and absorption contrast can be configured post-acquisition.
Feasibility study results indicate successful quantitative 3D imaging capabilities.

Conclusions:

The developed SIXM system provides a versatile platform for quantitative 3D X-ray micro-imaging.
The hybrid optical design offers flexibility in imaging modes and data acquisition.
This technology holds promise for various applications requiring high-resolution 3D structural information.