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Updated: May 8, 2026

Electrophysiological Methods to Assess Peripheral Pain Block in an Anesthetized Rat
Published on: November 21, 2025
The nerve compression block technique
1a Departments of Physiology and Psychology , University of Western Australia.
Abstract:
In a study by Kelso, Stelmach, and Wanamaker (1974), data were presented showing a progressive decrement in electromyographic responses to supramaximal whole-nerve stimulation with the development of ischemia-induced anoxia. Accordingly, they questioned the suitability of employing ischemia-induced anesthesia (nerve compression block) in the study of movement control. In the present paper issues relating to the review of existing literature, the methodology employed and the conclusions reached in the Kelso et al. study are discussed.
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