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Published on: February 6, 2021
Chronic postoperative Mycobacterium gordonae endophthalmitis in a patient with phakic intraocular lens
Cristobal Couto1, Silvia Rossetti, Ariel Schlaen
1Uveitis Clinic, University of Buenos Aires , Buenos Aires , Argentina .
Methods:
Case description of a 34 year old woman with chronic granulomatous anterior uveitis following implantation of a phakic anterior chamber intraocular lens (IOL). Aqueous humor was processed for bacterial, fungal culture, and PCR analysis.
Results:
PCR for 16S ribosomal RNA universal primers was positive and Southern-blot for Propionibacterium spp was negative. Panfungal PCR was negative. Growth of a pigmented yellow colony was detected on Lowenstein-Jensen medium. The isolate was subsequently identified as Mycobacterium gordonae. The patient was treated for atypical mycobacteria as well as an intracameral injection of moxifloxacin, with resolution of inflammation and improvement in visual acuity.
Conclusions:
This is the first reported case of Mycobacterium gordonae chronic postoperative endophthalmitis, and of chronic endophthalmitis following phakic IOL surgery. PCR and cultures were invaluable in making the diagnosis.
Insights
A rare case of chronic endophthalmitis caused by Mycobacterium gordonae after phakic intraocular lens (IOL) surgery was successfully treated. Diagnostic PCR and cultures confirmed the atypical mycobacterial infection, leading to improved vision.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Microbiology
Background:
- Chronic granulomatous anterior uveitis can occur after anterior chamber intraocular lens (IOL) implantation.
- Prompt diagnosis and treatment are crucial for managing postoperative endophthalmitis.
Observation:
- A 34-year-old woman developed chronic uveitis post-phakic IOL surgery.
- Aqueous humor analysis included bacterial, fungal cultures, and PCR.
Findings:
- PCR identified Mycobacterium gordonae, an atypical mycobacterium, as the causative agent.
- Standard bacterial and fungal tests were negative.
- Treatment with atypical mycobacterial medication and intracameral moxifloxacin resolved inflammation and improved visual acuity.
Implications:
- This is the first reported case of Mycobacterium gordonae causing chronic endophthalmitis after phakic IOL surgery.
- Molecular methods (PCR) and cultures are essential for diagnosing rare causes of endophthalmitis.
- Effective treatment strategies exist for this challenging condition.
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