Chronic postoperative Mycobacterium gordonae endophthalmitis in a patient with phakic intraocular lens

Cristobal Couto1, Silvia Rossetti, Ariel Schlaen

  • 1Uveitis Clinic, University of Buenos Aires , Buenos Aires , Argentina .

Abstract

Insights

A rare case of chronic endophthalmitis caused by Mycobacterium gordonae after phakic intraocular lens (IOL) surgery was successfully treated. Diagnostic PCR and cultures confirmed the atypical mycobacterial infection, leading to improved vision.

Area of Science:

  • Ophthalmology
  • Infectious Diseases
  • Microbiology

Background:

  • Chronic granulomatous anterior uveitis can occur after anterior chamber intraocular lens (IOL) implantation.
  • Prompt diagnosis and treatment are crucial for managing postoperative endophthalmitis.

Observation:

  • A 34-year-old woman developed chronic uveitis post-phakic IOL surgery.
  • Aqueous humor analysis included bacterial, fungal cultures, and PCR.

Findings:

  • PCR identified Mycobacterium gordonae, an atypical mycobacterium, as the causative agent.
  • Standard bacterial and fungal tests were negative.
  • Treatment with atypical mycobacterial medication and intracameral moxifloxacin resolved inflammation and improved visual acuity.

Implications:

  • This is the first reported case of Mycobacterium gordonae causing chronic endophthalmitis after phakic IOL surgery.
  • Molecular methods (PCR) and cultures are essential for diagnosing rare causes of endophthalmitis.
  • Effective treatment strategies exist for this challenging condition.

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