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Combinatorial Synthesis of and High-throughput Protein Release from Polymer Film and Nanoparticle Libraries
Published on: September 6, 2012
Release of guests from encapsulated masked hydrophobic precursors by a phototrigger
Nithyanandhan Jayaraj1, Pradeepkumar Jagadesan, Shampa R Samanta
1Department of Chemistry, University of Miami, Coral Gables, Florida 33124, USA.
Organic Letters
|August 29, 2013
Abstract:
Examples of release of organic acids from encapsulated p-methoxyphenacyl esters provided here demonstrate the value of a phototrigger strategy to release chemicals of interest in water from hydrophobic precursors. In this study, a photochemical β-cleavage process centered on the p-methoxyphenacyl group is exploited to release the acid of interest from a water-soluble capsule made up of octa acid.

