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Updated: May 8, 2026
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Gradient Strain Chip for Stimulating Cellular Behaviors in Cell-laden Hydrogel
Published on: August 8, 2017
Biochemical and physical signal gradients in hydrogels to control stem cell behavior
Oju Jeon1, Daniel S Alt, Stephen W Linderman
1Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH 44106, USA.
Advanced Materials (Deerfield Beach, Fla.)
|August 29, 2013
Abstract:
Three-dimensional (3D) gradients of biochemical and physical signals in macroscale degradable hydrogels are engineered that can regulate photoencapsulated human mesenchymal stem cell (hMSC) behavior. This simple, cytocompatible, and versatile gradient system may be a valuable tool for researchers in biomaterials science to control stem cell fate in 3D and guide tissue regeneration.
