Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Allergic Reactions

Allergic Reactions

Atypical Pneumonia

Atypical Pneumonia

Atypical pneumonia, often caused by Mycoplasma pneumoniae, is a form of pulmonary infection that differs from the classical presentation of bacterial pneumonia in both its cause and clinical symptoms. Mycoplasma pneumoniae is a pleomorphic bacterium notable for its lack of a rigid cell wall. This structural characteristic imparts resistance to beta-lactam antibiotics and significantly influences the bacterium’s behavior within the human host.Other pathogens responsible for the disease include...

Asthma I: Introduction

Asthma I: Introduction

Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...

Allergic Drug Reactions

Allergic Drug Reactions

Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing numerous...

Asthma III: Clinical Manifestations

Asthma III: Clinical Manifestations

Asthma presents with a characteristic pattern of episodic respiratory symptoms that reflect underlying airway inflammation, bronchoconstriction, and mucus hypersecretion. Although severity varies among individuals, certain clinical manifestations are considered hallmarks of the disorder and often guide diagnosis and assessment.Respiratory SymptomsA persistent cough is one of the most common early features of asthma. It is frequently dry and tends to worsen at night or in the early morning,...

Hypersensitivity Reactions: Delayed Hypersensitivity Reactions

Hypersensitivity Reactions: Delayed Hypersensitivity Reactions

Delayed-Type Hypersensitivity (DTH), or Type IV hypersensitivity, is a cell-mediated immune response. It occurs when T cells, rather than antibodies, mediate a reaction to specific antigens. It is characterized by a delayed onset (1-2 days) and involves the recruitment of macrophages to the inflammation site.The initiation of a DTH response begins with the sensitization of T cells. During this phase, which lasts at least 1-2 weeks, antigen-specific T cells are activated, clonally expanded, and...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Tardive Oromandibular Dystonia Associated With Long-Term Intermittent Use of Lurasidone.

Journal of clinical psychopharmacology·2026

Same author

Association Between Baseline Depressive Symptoms and Clinical Characteristics, Biomarker Profiles, and Clinical Outcomes in Patients With Peripheral Arterial Disease Undergoing Revascularization: A Prospective Cohort Study.

Cureus·2026

Same author

Beyond Principles: A Reflective-Cognitive Framework for Ethical Decision-Making in Anorexia Nervosa.

Healthcare (Basel, Switzerland)·2026

Same author

Long-term regular follow-up yields important benefits in forensic psychiatric patients with psychosis: A 2-year longitudinal study on psychopathology, general health, quality of life, and functioning.

Journal of forensic sciences·2026

Same author

Disrupted beginnings: Neurodevelopmental outcomes of COVID-19 lockdowns in early childhood (Review).

Experimental and therapeutic medicine·2026

Same author

Janus kinase/signal transducer and activator of transcription pathway in schizophrenia (Review).

Biomedical reports·2025

Search research articles

Related Experiment Video

Updated: May 8, 2026

Three-Dimensional Cell Culture Models to Investigate the Epithelial Barrier in Eosinophilic Esophagitis

Three-Dimensional Cell Culture Models to Investigate the Epithelial Barrier in Eosinophilic Esophagitis

Published on: May 10, 2024

Risperidone-induced acute eosinophilic pneumonia.

Emmanouil Rizos¹, Evdoxia Tsigkaropoulou, Panagiota Lambrou

¹Second Department of Psychiatry, Medical School, University of Athens, Attikon University General Hospital, Athens, Greece. erizos@med.uoa.gr

In Vivo (Athens, Greece)

|August 31, 2013

Summary

This summary is machine-generated.

This case report details the first instance of acute eosinophilic pneumonia (AEP) linked to risperidone, an atypical antipsychotic. Drug cessation led to rapid symptom resolution, highlighting risperidone as a probable cause.

Keywords:

Risperidone acute eosinophilic pneumonia serotonin

More Related Videos

Self-Administration of Drugs in Mouse Models of Feeding and Obesity

Self-Administration of Drugs in Mouse Models of Feeding and Obesity

Published on: June 8, 2021

Related Experiment Videos

Last Updated: May 8, 2026

Three-Dimensional Cell Culture Models to Investigate the Epithelial Barrier in Eosinophilic Esophagitis

Three-Dimensional Cell Culture Models to Investigate the Epithelial Barrier in Eosinophilic Esophagitis

Published on: May 10, 2024

Self-Administration of Drugs in Mouse Models of Feeding and Obesity

Self-Administration of Drugs in Mouse Models of Feeding and Obesity

Published on: June 8, 2021

Area of Science:

Pulmonology
Pharmacology
Toxicology

Background:

Acute eosinophilic pneumonia (AEP) is a severe respiratory condition potentially triggered by various factors, including medications.
While drug-induced AEP is documented, associations with second-generation antipsychotics like risperidone have not been previously reported.

Observation:

A 64-year-old male patient developed acute respiratory distress following low-dose risperidone treatment for paranoid symptoms.
Diagnostic evaluation, including bronchoalveolar lavage (BAL), confirmed AEP.
All clinical evidence pointed towards risperidone as the likely causative agent.

Findings:

The patient's AEP symptoms resolved rapidly upon discontinuation of risperidone.
Pathophysiological analysis suggests a role for eotaxin and serotonin in mediating AEP through risperidone's serotoninergic activity.

Implications:

This case represents the first reported instance of AEP associated with an atypical antipsychotic (risperidone).
The findings suggest a need for increased awareness of AEP as a potential adverse reaction to risperidone and similar agents.
Understanding the mechanisms involving eotaxin and serotonin may inform future management strategies for drug-induced AEP.