Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: May 8, 2026

Construction of a Preclinical Multimodality Phantom Using Tissue-mimicking Materials for Quality Assurance in Tumor Size Measurement
06:33

Construction of a Preclinical Multimodality Phantom Using Tissue-mimicking Materials for Quality Assurance in Tumor Size Measurement

Published on: July 29, 2013

Solid anthropomorphic infant whole-body DXA phantom: design, evaluation, and multisite testing.

Roman J Shypailo1, Kenneth J Ellis

  • 1US Department of Agriculture/Agricultural Research Service Children's Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, Texas.

Pediatric Research
|September 4, 2013
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Adverse effect of obesity and dysglycemia on bone microarchitecture and strength in youth: sex-related differences.

The Journal of clinical endocrinology and metabolism·2026
Same author

High-resolution peripheral quantitative computed tomography reliability and accuracy of bone density and morphology properties in children.

JBMR plus·2025
Same author

Comparison of percentile tables and algorithm-based calculators for classification of blood pressures in children and adolescents with obesity: A secondary analysis of a clinical trial.

Journal of paediatrics and child health·2022
Same author

External validation of a prediction model for estimating fat mass in children and adolescents in 19 countries: individual participant data meta-analysis.

BMJ (Clinical research ed.)·2022
Same author

Genetic variants and physical activity interact to affect bone density in Hispanic children.

BMC pediatrics·2021
Same author

Characterization of the Robinow syndrome skeletal phenotype, bone micro-architecture, and genotype-phenotype correlations with the osteosclerotic form.

American journal of medical genetics. Part A·2020
Same journal

Choice, confounding, and consequence: twenty years of empiric antibiotics for neonatal early-onset sepsis.

Pediatric research·2026
Same journal

Comparing in-person and online recruitment methods in a prospective pediatric cohort study.

Pediatric research·2026
Same journal

Craniosynostosis and neurodevelopment: reframing a surgical condition as a global developmental risk.

Pediatric research·2026
Same journal

Neurologic sequelae of cerebral malaria and other forms of severe malaria in children.

Pediatric research·2026
Same journal

Home and in-hospital phototherapy as comparable select routine approach for neonatal hyperbilirubinemia.

Pediatric research·2026
Same journal

Polycyclic aromatic hydrocarbons and perinatal outcomes: a scoping review.

Pediatric research·2026
See all related articles

A new dual-energy X-ray absorptiometry (DXA) phantom for infants shows good reproducibility. However, significant differences between DXA instruments emphasize the need for cross-calibration in multicenter infant body composition studies.

Area of Science:

  • Medical imaging
  • Biomedical engineering
  • Pediatric research

Background:

  • Dual-energy X-ray absorptiometry (DXA) is crucial for quality control and cross-calibration.
  • Existing phantoms are not designed for infant whole-body scanning.
  • Accurate infant body composition assessment is vital for pediatric health studies.

Purpose of the Study:

  • To develop and evaluate a novel phantom for infant whole-body DXA scanning.
  • To assess the comparability of DXA instruments in infant body composition analysis.
  • To address the lack of specialized phantoms for pediatric DXA applications.

Main Methods:

  • A custom phantom was fabricated using polyvinyl chloride (PVC), nylon mix, and polyethylene to mimic infant bone, lean tissue, and fat.

More Related Videos

Multimodal 3D Printing of Phantoms to Simulate Biological Tissue
05:11

Multimodal 3D Printing of Phantoms to Simulate Biological Tissue

Published on: January 11, 2020

Assessment of Child Anthropometry in a Large Epidemiologic Study
09:36

Assessment of Child Anthropometry in a Large Epidemiologic Study

Published on: February 2, 2017

Related Experiment Videos

Last Updated: May 8, 2026

Construction of a Preclinical Multimodality Phantom Using Tissue-mimicking Materials for Quality Assurance in Tumor Size Measurement
06:33

Construction of a Preclinical Multimodality Phantom Using Tissue-mimicking Materials for Quality Assurance in Tumor Size Measurement

Published on: July 29, 2013

Multimodal 3D Printing of Phantoms to Simulate Biological Tissue
05:11

Multimodal 3D Printing of Phantoms to Simulate Biological Tissue

Published on: January 11, 2020

Assessment of Child Anthropometry in a Large Epidemiologic Study
09:36

Assessment of Child Anthropometry in a Large Epidemiologic Study

Published on: February 2, 2017

  • The phantom underwent short- and long-term repeatability scans.
  • The phantom was cross-scanned across six different sites using Hologic DXA instruments.

    • Main Results:

    • The phantom demonstrated good short- and long-term reproducibility for lean mass, bone, and fat.
    • Material compositions showed slight under- or overrepresentation of target tissues (lean: -5%, bone: -12%, fat: +30%).
    • Significant inter-instrument variability was observed in bone mineral content, bone density, fat, and lean mass measurements.

    Conclusions:

    • The developed infant phantom effectively emulates key body tissues and exhibits good reproducibility.
    • Substantial differences between DXA instruments necessitate rigorous cross-calibration for multicenter infant body composition studies.
    • This phantom serves as a valuable tool for improving the reliability of pediatric DXA assessments.