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Leser-Trélat sign: does it really exist?
Enver Turan1, Yavuz Yesilova, Nurdan Yurt
1Department of Dermatology, Faculty of Medicine, University of Harran, 63200-Sanliurfa, Turkey. enverturan@gmail.com
Acta Dermatovenerologica Croatica : ADC
|September 5, 2013
Summary
The Leser-Trélat sign, characterized by sudden seborrheic keratosis growth, can occur without malignancy. This case highlights the ongoing debate about its paraneoplastic nature.
Area of Science:
- Dermatology
- Oncology
Background:
- The Leser-Trélat sign is a rare condition involving the sudden onset and rapid growth of seborrheic keratoses.
- It is often associated with internal malignancies, particularly adenocarcinomas and lymphomas, suggesting a potential paraneoplastic phenomenon.
Observation:
- This report details a patient presenting with the Leser-Trélat sign.
- Despite thorough medical examinations and an 18-month follow-up period, no underlying malignancy was detected in this individual.
Findings:
- The case challenges the definitive classification of the Leser-Trélat sign as exclusively a paraneoplastic syndrome.
- It underscores the importance of comprehensive evaluation while acknowledging potential idiopathic presentations.
Implications:
- Further research is needed to elucidate the exact pathophysiology and diagnostic criteria for the Leser-Trélat sign.
- This case contributes to the ongoing discussion regarding its association with cancer and the need for careful patient monitoring.
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