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[Eosinophilic fasciitis associated with Parkinson's syndrome - a case report]

Vesna Budisin1, Dragica Vrabec-Matković, Visnja Milavac-Puretić

  • 1Poliklinika Medikol, Zagreb. budisin.vesna@gmail.com

Reumatizam
|September 6, 2013
PubMed

Insights

A 67-year-old patient developed severe arm swelling, initially diagnosed as erysipelas and lymphedema. Later, eosinophilic fasciitis was diagnosed, leading to neurological and musculoskeletal complications despite treatment.

Area of Science:

  • Rheumatology
  • Infectious Diseases
  • Neurology

Background:

  • A 67-year-old male presented with right arm erythema and swelling.
  • Initial diagnoses included erysipelas and lymphedema, treated with antibiotics.

Observation:

  • The patient developed progressive neurological symptoms including dizziness, tremor, balance disorders, hearing impairment, and spinal pain.
  • Despite lymphatic drainage and antibiotic treatment, symptoms persisted and worsened.
  • Eosinophilic fasciitis was diagnosed in the seventh month, treated with corticosteroids.

Findings:

  • Corticosteroid therapy for eosinophilic fasciitis showed limited effect on neurological symptoms.
  • Levodopa and ropinirole were initiated for extrapyramidal syndrome, resulting in slight improvement.
  • After 18 months, the patient exhibited significant disability including contractures, tremors, balance issues, and mobility difficulties.

Implications:

  • This case highlights the complex and multisystemic nature of eosinophilic fasciitis.
  • Delayed diagnosis and treatment can lead to severe, irreversible neurological and musculoskeletal damage.
  • Further research into effective therapeutic strategies for eosinophilic fasciitis and its complications is warranted.

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