Topical application of antibiotics in primary teeth: an overview

Root canal infections are polymicrobial in nature, consisting of both aerobic and anaerobic species. The successful treatment of both primary and secondary endodontic infections involves effective eradication of the causative microorganisms during root canal treatment procedures. Reduction and elimination of microorganisms from the infected root canal provides optimal opportunity for treatment success. Local application of antibiotics has been considered an effective way to deliver antibiotics. A combination of antibiotic drugs have been tried under the concept of lesion sterilization and tissue repair therapy to eliminate the target bacteria, which are possible sources of endodontic lesions. The purpose of this article is to discuss the lesion sterilization and tissue repair therapy technique in primary teeth.