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Related Concept Videos

Alzheimer Disease ll: Pathophysiology01:23

Alzheimer Disease ll: Pathophysiology

Alzheimer disease involves structural changes in the brain that begin long before symptoms appear. The most distinctive features are extracellular neuritic plaques and intracellular neurofibrillary tangles.Neuritic plaques form in the cerebral cortex and around blood vessels. These plaques contain a dense core of beta-amyloid (Aβ)—a toxic protein fragment that clumps outside neurons. The core is surrounded by damaged neuronal extensions, as well as reactive astrocytes and microglia. Abnormal...
Alzheimer's Disease: Overview01:26

Alzheimer's Disease: Overview

Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ and tau...
Alzheimer Disease l: Introduction01:29

Alzheimer Disease l: Introduction

Alzheimer disease is a chronic, progressive, and irreversible neurodegenerative disorder and the most common cause of dementia in older adults. It leads to gradual neuronal loss, causing cognitive decline, behavioral changes, and loss of functional independence.Risk Factors and EtiologyThe disease is multifactorial. Age is the strongest risk factor, with prevalence doubling every 5 years after age 65. Genetic factors include mutations in genes such as APP, PSEN1, and PSEN2, which are associated...
Dementia l: Introduction01:22

Dementia l: Introduction

Dementia is an acquired, progressive syndrome characterized by a decline in multiple cognitive domains severe enough to impair daily functioning and reduce independence. Although memory loss is a central feature, the diagnosis requires additional deficits involving language, executive function, visuospatial skills, judgment, calculation, or abstract reasoning. These cognitive impairments reflect underlying neurodegenerative or vascular processes that gradually disrupt neuronal networks...
Alzheimer's Disease: Treatment01:22

Alzheimer's Disease: Treatment

Alzheimer's Disease (AD), a neurodegenerative disorder, is pathologically identified by amyloid plaques and neurofibrillary tangles composed of tau protein. AD pharmacotherapy aims to manage cognitive symptoms, delay disease progression, and treat behavioral symptoms. The treatment is primarily symptomatic and palliative, with no definitive disease-modifying therapy available. Cholinesterase inhibitors, including donepezil (Aricept), rivastigmine (Exelon), and galantamine (Razadyne), are...
Dementia01:30

Dementia

Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual.

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Related Experiment Video

Updated: May 8, 2026

Examining the Characteristics of Episodic Memory using Event-related Potentials in Patients with Alzheimer's Disease
11:01

Examining the Characteristics of Episodic Memory using Event-related Potentials in Patients with Alzheimer's Disease

Published on: August 30, 2011

[Proceeding memory in Alzheimer's disease].

Eva Ma Arroyo-Anlló1, Jorge Chamorro-Sánchez, Juan Poveda Díaz-Marta

  • 1Departamento de Psicología, Univerisidad de Salamanca, Salamanca, Spain. anlioa@usal.es

Revista Medica Del Instituto Mexicano Del Seguro Social
|September 12, 2013
PubMed
Summary

Procedural learning, the unconscious skill acquisition, remains largely intact in Alzheimer's disease (AD). This preservation offers potential for rehabilitation strategies to enhance patient autonomy.

Keywords:
Alzheimer's diseasedemenciadementiaenfermedad de Alzheimermemoria implícitareaction timerehabilitaciónrehabilitationrepetition primingtiempo de reacción

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Last Updated: May 8, 2026

Examining the Characteristics of Episodic Memory using Event-related Potentials in Patients with Alzheimer's Disease
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Operation Procedure and Precautions of Thread-Embedding Acupuncture Therapy in Alzheimer
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Area of Science:

  • Neuroscience
  • Cognitive Psychology

Context:

  • Alzheimer's disease (AD) is a progressive neurodegenerative disorder impacting cognitive functions.
  • Procedural skills, acquired through repetition, are crucial for daily living and patient autonomy.

Purpose:

  • To review and analyze existing literature on procedural learning in Alzheimer's disease.
  • To assess the preservation of various procedural skills in AD patients.

Summary:

  • A review of 40 articles published over three decades examined motor, perceptual-motor, cognitive, and perceptual-cognitive skills, as well as those from serial reaction-time tasks.
  • The analysis focused on task-specific procedural skill evaluation and learning preservation in AD.
  • Findings indicate that procedural learning is generally conserved or relatively preserved in Alzheimer's disease.

Impact:

  • The conserved nature of procedural learning in AD presents a significant opportunity for developing effective neuropsychological rehabilitation interventions.
  • These interventions can potentially improve and maintain functional independence and autonomy for individuals with Alzheimer's disease.