Related Experiment Video
Updated: May 7, 2026
Alternative Therapy for Acute Exacerbation of Chronic Obstructive Pulmonary Disease: Moving Cupping Along Meridians
Published on: September 27, 2024
Association of chronic obstructive pulmonary disease with coronary artery disease
Bin-Miao Liang1, Zhi-Bo Xu, Qun Yi
1Department of Respiratory Medicine, West China Hospital of Sichuan University, Chengdu, Sichuan 610041, China.
Insights
Chronic obstructive pulmonary disease (COPD) is more common in patients with coronary artery disease (CAD). COPD is a significant risk factor for multi-vessel CAD, possibly due to systemic inflammation.
Area of Science:
- Cardiology
- Pulmonology
- Medical Imaging
Background:
- The link between chronic obstructive pulmonary disease (COPD) and coronary artery disease (CAD) is not well understood.
- This study investigates the association between COPD and CAD, particularly multi-vessel disease.
Purpose of the Study:
- To determine the prevalence of COPD in patients with suspected CAD.
- To explore the relationship between COPD and the extent of coronary artery disease, specifically multi-vessel disease.
Main Methods:
- Analysis of multi-detector computed tomography (MDCT) data from 354 patients with suspected CAD.
- Assessment of serum biochemistry, spirometry, and COPD diagnosis based on Global Initiative for Chronic Obstructive Lung Disease criteria.
- Definition of luminal narrowing as >= 50% stenosis.
Main Results:
- Patients with CAD had a significantly higher complication rate of COPD (11.8%) compared to those without CAD (3.7%).
- COPD patients were more likely to have multi-vessel disease, a history of smoking, and elevated C-reactive protein (CRP).
- Multivariate analysis showed multi-vessel disease was significantly correlated with COPD (P=0.012) and CRP (P=0.015).
Conclusions:
- COPD is highly prevalent in patients with CAD and may be a critical risk factor for developing multi-vessel CAD.
- CAD and COPD are closely associated, with systemic inflammation potentially mediating their relationship.
- These findings highlight the importance of considering COPD in CAD patients and vice versa.
Background:
The relationship between chronic obstructive pulmonary disease (COPD) and coronary artery disease (CAD) remains largely unknown. This study aimed to explore the association of COPD with CAD, especially with multi-vessel disease (VD).
Methods:
The data of 354 patients who underwent multi-detector computed tomography (MDCT) for suspected CAD were analyzed. Luminal narrowing was defined as at least one lesion 50% or greater stenosis. The analysis of serum biochemistry profile and spirometry were performed on all eligible patients, and the diagnosis of COPD was defined as the criteria of Global Initiative for Chronic Obstructive Lung Disease.
Results:
Patients with CAD had a significantly higher complication of COPD than those without CAD (11.8% vs. 3.7%, P < 0.001). Comparing with patients without COPD, those with COPD were more likely to have multi-VD, proportion of smoking and high C-reactive protein (CRP) (P < 0.001). Multivariate Logistic regression analysis revealed that the multi-VD was significantly correlated with COPD (P=0.012) and CRP (P=0.015).
Conclusions:
There was a high complication of COPD in patients with CAD, and COPD may be a critical risk factor for CAD, especially for multi-VD. CAD and COPD were closely associated and the interplay of systemic inflammation might in part explain the relationship between them.
More Related Videos
04:53Acupoint Application Combined with Ear Plaster Therapy for Treating Sleep Disorders with Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Published on: October 18, 2024
05:34Auricular Acupuncture as a Traditional Chinese Medicine Therapy for Chronic Obstructive Pulmonary Disease Combined with Sleep Disorders
Published on: August 18, 2023
Related Concept Videos
01:24Chronic Obstructive Pulmonary Disease
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
01:23Chronic Obstructive Pulmonary Disease I: Introduction
01:20Chronic Obstructive Pulmonary Disease-I: Introduction
01:25Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
01:20Chronic Obstructive Pulmonary Disease-II: Pathophysiology
Chronic Inflammation
01:24Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features