Changing the mind? Not really-activity and connectivity in the caudate correlates with changes of choice
Takehito Ito1, Daw-An Wu1, Toshiyuki Marutani1
1Brain Science Institute, Tamagawa University, 6-1-1, Tamagawa Gakuen, Machida, Tokyo 194-8610, Japan, Division of Biology/Option Representative, Computation and Neural Systems, California Institute of Technology, 139-74, Pasadena, CA 91125, USA, and Department of Pharmacology, Nippon Medical School, 1-1-5, Sendagi, Bunkyo-ku, Tokyo 113-8602, Japan.
Abstract:
Changes in preference are inherently subjective and internal psychological events. We have identified brain events that presage ultimate (rather than intervening) choices, and signal the finality of a choice. At the first exposure to a pair of faces, caudate activity reflected the face of final choice, even if an initial choice was different. Furthermore, the orbitofrontal cortex and hippocampus exhibited correlations only when the subject had made a choice that would not change.
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