Related Experiment Video
Updated: May 7, 2026

05:14
Comparison of Agreement and Accuracy using Binocular Wavefront Optometer with Autorefractor and Phoropter
Published on: September 16, 2025
Crystalens HD intraocular lens analysis using an adaptive optics visual simulator.
Cari Pérez-Vives1, Robert Montés-Micó, Norberto López-Gil
1*MSc †PhD GIO, Optics Department, Faculty of Physics, University of Valencia, Valencia, Spain (CP-V, RM-M, TF-B, SG-L); and Escuela de Óptica y Optometría, University of Murcia, Murcia, Spain (NL-G).
Summary
The Crystalens HD intraocular lens (IOL) offers visual and optical quality comparable to monofocal IOLs. With accommodative movement, it shows potential for high-quality near vision, enhancing visual outcomes.
Area of Science:
- Ophthalmology
- Optical Engineering
- Biomedical Engineering
Background:
- Intraocular lenses (IOLs) are crucial for vision restoration after cataract surgery.
- Accommodating IOLs aim to mimic the natural eye's focusing ability.
- Comparing the performance of advanced IOL designs with traditional ones is essential.
Purpose of the Study:
- To compare the visual and optical quality of the Crystalens HD accommodating intraocular lens (IOL) against a standard monofocal IOL.
- To evaluate the impact of the Crystalens HD IOL's accommodative movement on visual performance.
Main Methods:
- Wavefront aberrations and optical quality metrics (MTF, PSF, Strehl ratio) were measured in a model eye for both IOLs.
- Visual acuity (distance and near) and contrast sensitivity were assessed under various lighting conditions and pupil sizes.
- The Crystalens HD IOL was tested in both non-accommodative and accommodative (1.4 mm movement) states.
Main Results:
- The Crystalens HD IOL demonstrated optical quality (MTF, PSF, Strehl ratio) comparable to the monofocal IOL.
- No significant differences in distance visual acuity or contrast sensitivity were found between the IOLs.
- The Crystalens HD IOL provided a depth of focus of approximately 0.75 D (accommodative) and 0.50 D (non-accommodative).
Conclusions:
- The non-accommodated Crystalens HD IOL offers visual and optical performance equivalent to monofocal IOLs.
- The potential 1.4 mm accommodative movement suggests the Crystalens HD IOL can provide high-quality near vision.
- Further in-vivo studies are warranted to confirm these findings in patients.
